estrogen

Dr. David Zava, ZRT Laboratory President, talks about the balance of progesterone and estrogen, its importance to women's health, and risk of breast cancer.

Dr. David Zava, President of ZRT Laboratory, lectures on the importance of estrogen in women's health.

Diana Woodruff-Pak (Temple University, Philadelphia, PA) used cholesterol-fed rabbits as a model of AD for evaluation of currently available and potential anti-Alzheimer drugs. These animals developed typical Alzheimer pathology, including behavioral changes and deposition of ß-amyloid and even tau. Galantamine and donepezil partially protected animals from Alzheimer symptomatology.

Michael Rogawski (University of California, Davis) summarizes his research on the antiepileptic activity of neurosteroids (e.g. ganaxolone, allopregnanolone). They are allosteric modulators of GABAA receptors and are active in many models of epilepsy. They are expected, however, to be most effective in catamenial epilepsy, infantile spasms or adult partial seizures. National Institutes of Health (NIH) is currently sponsoring a clinical trial of progesterone (precursor of allopregnanolone)...