Role of the Neural Crest in Vertebrate Development and Evolution by Nicole Le Douarin, March 2008 - Part 1: The Quail Chick Marker System and Its Use to Study the Ontogeny of the Neural Crest (24:45)

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The neural crest (NC) is a transitory structure of the Vertebrate embryo. It forms when the neural tube closes through the epithelio- mesenchymal transition of the cells in the joining neural folds. Its constitutive cells are endowed of migratory capacities and are highly pluripotent. NC cells migrate in the developing embryo along definite pathways, at precise periods of time during embryogenesis and settle in elected sites in the body where they develop into a large of cell types. The...