Epizyme - HMT "Tree" Presentation Video

submitted by: Epizyme
A survey of the human genome was performed to understand the constituency of protein methyltransferases (both protein arginine and lysine methyltransferases) and the relatedness of their catalytic domains. We identified 51 protein lysine methyltransferase proteins based on similarity to the canonical Drosophila Su(var)3-9, enhancer of zeste (E(z)), and trithorax (trx) domain. Disruptor of telomeric silencing-1-like, a known protein lysine methyltransferase, did not fit within the protein...
Authors: Christopher Sneeringer, Margaret Scott, Keith Elliston, Danielle Johnston, Lei Jin, L. fred Jerva, Victoria Richon, Robert Copeland, Christina Majer

Video demo on Human Epigenome Browser

submitted by: Xin Zhou

The Human Epigenome Browser is an advanced web service that allows investigators to navigate and explore Roadmap Epigenomics project data set, and much more! This video clip briefly goes over main features of our web service. Visit the browser at http://vizhub.wustl.edu/. This video clip was made by Brett Maricque.

Epigenetic Landscapes

submitted by: BenPaylor
Conrad, a scientist at the University of Calgary, travels from Calgary to Vancouver to see his identical twin brother Hal. Hal is an alcoholic and has been admitted to the hospital with a failing liver. As Conrad and his cameraman drive through the Rockies, Conrad discusses with the cameraman the basics of epigenetics and how accumulated epigenetic changes can lead to differences between identical twins. The film aims to investigate the concept of “nature versus nurture” as described by...

Welcome to Next-Generation Sequencing 2008 Conference

submitted by: dougramsey
Calit2's Center for Algorithmic and Systems Biology (CASB) recently hosted the UC San Diego Next-Generation Sequencing and Informatics Symposium. The Nov. 9-10 meeting provided an introduction to next-generation sequencing techniques, along with reports on the latest data analysis algorithms and tools. The first day focused on resequencing and de novo sequencing, and the algorithmic developments that are driving the increase in data quality and volume in this field. On day two, the focus...