Clathrin-mediated endocytosis regulates occludin, and not focal adhesion, distribution during epithelial wound healing

submitted by: RappoportLab
BACKGROUND INFORMATION: Vesicle trafficking has long been suggested to play mechanistic roles in regulating directed cell migration. Recent evidence demonstrates that specific cell types and modes of migration involve transport of particular cargo through particular pathways. Epithelial wound healing is essential in tissue repair. However, investigations into the mechanisms regulating cell migration have mainly focused upon other models such as fibroblast-derived cells. Roles for vesicle...
Authors: Sarah Fletcher, Natalie Poulter, Elizabeth Haining, Joshua Rappoport