Electrostatics and long-range coupling in Src kinase activation

submitted by: icamvid

Carol Post gives a talk at the RPP08 conference on Src, a mechanism of conformational activation. She covers two topics regarding it Src:
1) Switched electrostatic network
2) long-range coupling of regulatory SH2/SH3 and catalytic domain

Dynamics of Large-Scale Domain Motions in Protein Kinase A

submitted by: icamvid

Don Blumenth gives a talk at the RPP08 conference about the application of SAXS small-angle scattering to study the domain motions in Protein Kinase A and other protein kinases specifically in response to cAMP.