Dr. John Davis, III, Assistant Professor of Medicine in Rheumatology at Mayo Clinic in Rochester, MN, discusses his article appearing in the July 2012 issue of Mayo Clinic Proceedings, that recounts a state-of-the art treatment approach to rheumatoid arthritis using algorithms, individualized treatments, and endpoints. Available at: http://www.mayoclinicproceedings.org/article/S0025-6196(12)00472-7/fulltext.