Single molecule analyses of DNA in environmental microbes

submitted by: dougramsey
Comprehensive characterization of genomic composition in environmental microbial samples has been challenging, because the majority of microorganisms are difficult to culture. Additional challenges include a high degree of genetic diversity between and within species, various level of relative abundance and ubiquitous presence of cell-free DNA. Single cells or single molecules genomic assays hold great promise for tackling these challenges. Recent progresses in the developments of these...

The Importance of Marine Picoeukaryotes and the Search for Lost Time

submitted by: dougramsey
Unicellular eukaryotes are responsible for a massive amount of photosynthetic carbon fixation in marine systems. The smallest among these fall within the “pico” size fraction (<2 micrometers in diameter), are broadly distributed – from coastal to open-ocean environments – and are highly diverse. Picoeukaryotes contribute a significant proportion of the biomass and primary production within this size fraction, often rivaling their cyanobacterial counterparts Prochlorococcus and...

Deep-Ocean Metagenomics: Comparative Investigations of Microbes Inhabiting Hydrothermal Vents and the Cold Deep Ocean

submitted by: dougramsey
The deep-ocean accounts for the majority of the water on our planet. While the cold deep-ocean is the dominant nutrient-challenged ecosystem, hydrothermal vents represent oases along tectonically active areas of the seafloor. Hydrothermal vents and the surrounding cold deep-ocean each support unique communities of microbes and viruses that have become highly adapted to local conditions. Through cycles of infection and host cell lysis, bacteriophages (viruses that specifically infect...

Analyzing the Mobile Metagenome

submitted by: dougramsey
Metagenomic approaches are being use to investigate many diverse ecosystems and reveal many novel functions therein. However these methods can frequently pass over the DNA which we find in the mobile metagenome or mobilome. Much of this DNA is not easily cloned into fosmids or BACs for functional analysis and DNA based metagenomics projects do not always provide sufficient information to determine from where the sequence arose, genome or mobilome. Couple these limitations to the fact that...

Diversity Profile of the Human Skin Microbiome in Health and Disease Elizabeth A. Grice, National Institutes of Health

submitted by: dougramsey

Elizabeth A. Grice of National Institutes of Health discusses "Diversity Profile of the Human Skin Microbiome in Health and Disease"

The Human Oral Microbiome by Floyd Dewhirst, Harvard University

submitted by: dougramsey
The human oral cavity is a diverse habitat that contains approximately bacterial 600 predominant species. The oral microbiome is comprised of 44% named species, 12% isolates representing unnamed species, and 44% phylotypes known only from 16S rRNA based cloning studies. Species from 11 phyla have been identified: Firmicutes (211), Bacteroidetes (106), Proteobacteria (99), Actinobacteria (64), Spirochaetes (49), Fusobacteria (29), TM7 (12), Synergistetes (10), Chlamydiae (1), Chloroflexi (1)...

SDSU Geological Sciences Webinar - Stephen T. Hasiotis

submitted by: tcarrasc
Ichnology for the 21st Century: Understanding the differences between continental and marine trace fossils, with implications to the diversity, distribution, and evolution of soil biota ; Department of Geological Sciences, San Diego State University, Seminar Series ; The study of ichnology has come a long way since its inception and it continues to evolve. In particular, progress is being made in understanding the implications of trace fossils in the continental realm and how they can be...

Alzheimer's Disease

submitted by: alex01
Z. Khachaturian, PhD. - New approaches to the therapy of Alzheimer’s disease (AD) are discussed in video interviews of this series. According to Z. Khachaturian (Potomac, MD) substantial progress has been made during the last 10 years in our understanding of pathogenesis of Alzheimer’s disease as well as in the discovery of biomarkers and therapeutic approaches. In addition to cholinergic drugs, inhibitors of plaque formation have been discovered, but the currently available...

Apparency and Actuality

submitted by: hsrikm
Apparency and actuality are discussed with respect to science, genetics, evolution, cognition and perception. Rules for a (sub)set of actual/allowable sets of entities and objects from a total set that is based on differences and contrasts extracted from perceptual experience of the world elucidate tenable combinations/recombinations from a total of the transparent(history/past dependant) and the apparent as they can be construed to comprise the actual/real faces of perception. The elements...

Talk by Jim Nelson

submitted by: dougramsey

Jim Nelson talks about what needs to be done to help the learning gaps in children of different backgrounds be bridged and points out that one of the causes of the problem is the competency of the teaching staff in terms of education and pedagogic skills.