Glucose - Sweet Side of Chemistry

submitted by: nsf
Glucose, the simplest sugar, can be found in plants and is absorbed into bloodstreams during digestion. While most of us can be blissfully ignorant of our exact blood sugar levels after scarfing a Snickers, people who have diabetes or physicians with seriously injured patients need technology that provides accurate blood glucose data. Gymama Slaughter, an NSF-funded engineer at the University of Maryland Baltimore County, has created a new wireless, implantable sensor to monitor blood...

Health effect of the New Nordic Diet in adults with increased waist circumference: a 6-mo randomized controlled trial.

submitted by: skp
BACKGROUND: The regional Mediterranean Diet has been associated with lower risk of disease. OBJECTIVE: We tested the health effects of the New Nordic Diet (NND), which is a gastronomically driven regional, organic, and environmentally friendly diet, in a carefully controlled but free-living setting. DESIGN: A total of 181 centrally obese men and women, with a mean (range) age of 42 y (20-66 y), body mass index (in kg/m(2)) of 30.2 (22.6-47.3), and waist circumference of 100 cm (80-138...
Authors: Sanne Kellebjerg Poulsen, Anette Due, Andreas Jordy, Bente Kiens, Ken D Stark, Steen Stender, Claus Holst, Arne Astrup, Thomas Meinert Larsen

Active Travel to Work and Cardiovascular Risk Factors in the United Kingdom

submitted by: samwong
Background: Increasing active travel (walking, cycling, public transport) is increasingly seen as integral to strategies to raise physical activity levels. Purpose: This study examined (1) sociodemographic correlates of active travel to work and (2) associations between active travel and cardiovascular risk factors in the United Kingdom (UK). Methods: Data come from Understanding Society, a nationally representative survey of UK residents in 2009/2011, analyzed in 2012. Multinomial...
Authors: Anthony Laverty, Jennifer Mindell, Elizabeth Webb, Christopher Millett

Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence

submitted by: WSB
Background: Periodontal disease and diabetes mellitus are common, chronic diseases worldwide. Epidemiologic and biologic evidence suggests periodontal disease may affect diabetes. Objective: To systematically review non-experimental, epidemiologic evidence for effects of periodontal disease on diabetes control, complications, and incidence. Data sources: Electronic bibliographic databases, supplemented by hand searches of recent and future issues of relevant journals. Study eligibility...
Authors: Wenche S. Borgnakke, Pekka V. Ylostalo, George W. Taylor, Robert R. Genco

Is there a dose-response relation of dietary glycemic load to risk of type 2 diabetes? Meta-analysis of prospective cohort studies

submitted by: Geoffrey Livesey
Background: Although much is known about the association between dietary glycemic load (GL) and type 2 diabetes (T2D), prospective cohort studies have not consistently shown a positive dose-response relation. Objective: We performed a comprehensive examination of evidence on the dose response that links GL to T2D and sources of heterogeneity among all prospective cohort studies on healthy adults available in the literature. Design: We conducted a systematic review of all prospective...
Authors: Geoffrey Livesey, Richard Taylor, Helen Livesey, Simin Liu

Online Disease Management of Diabetes: (EMPOWER-D)

submitted by: Jamia
Full title: Online Disease Management of Diabetes: Engaging and Motivating Patients Online With Enhanced Resources-Diabetes (EMPOWER-D), A Randomized Controlled Trial Abstract: OBJECTIVE: To evaluate an online disease management system supporting patients with uncontrolled type 2 diabetes. MATERIALS AND METHODS: Engaging and Motivating Patients Online With Enhanced Resources for Diabetes was a 12-month parallel randomized controlled trial of 415 patients with type 2 diabetes with...

How Insulin Works

submitted by: trevbt

Scientific American entry for Iron Egg Head demonstrating how insulin works in the body.

SciAm2012

Dietary Selenium Deficiency Partially Rescues Type 2 Diabetes–Like Phenotypes of Glutathione Peroxidase-1–Overexpressing Male Mice

submitted by: xlei
This study was conducted to determine whether dietary Se deficiency precluded overproduction of glutathione peroxidase-1 (GPX1) activity in mice overexpressing (OE) this gene and thus rescued their type 2 diabetes–like phenotypes. A total of 20 male OE and wild-type (WT) mice were fed an Se-deficient (<0.02 mg/kg) diet or an Se-supplemented (0.3 mg/kg as sodium selenite) diet from 1 to 5 mo of age. Dietary Se deficiency eliminated or attenuated (P < 0.05) genotype differences in...
Authors: Xin Gen Lei, Li Li, Matt Pepper, Carol Roneker, Marko Vatamaniuk, Xi Yan

Antidiabetics Video Consult

submitted by: Rxconsultnow

This video will provide information on antidiabetics, specifically metformin.

Visit our website at www.rxconsultnow.com

Prolonged Dietary Selenium Deficiency or Excess Does Not Globally Affect Selenoprotein Gene Expression and/or Protein Production in Various Tissues of Pigs

submitted by: leilab
We previously determined the effects of dietary selenium (Se) de?ciency or excess on mRNA abundance of 12 selenoprotein genes in pig tissues. In this study, we determined the effect of dietary Se on mRNA levels of the remaining porcine selenoprotein genes along with protein production of 4 selenoproteins (Gpx1, Sepp1, Selh, and Sels) and body glucose homeostasis. Weanling male pigs (n = 24) were fed a Se-de?cient (,0.02 mg Se/kg), basal diet supplemented with 0, 0.3, or 3.0 mg Se/kg as...
Authors: Yan Liu, Hua Zhao, Qiaoshan Zhang, Jiayong Tang, Ke Li, Xin-Jie Xia, Kang-Ning Wang, Kui Li, Xin Gen Lei