MyD88 knockout mice develop initial enlarged periapical

AIM: To characterize the formation and progression of experimentally induced periapical lesions in teeth of MyD88 knockout (MyD88 KO) mice compared with wild-type (WT) mice. METHODOLOGY: Periapical lesions were induced in the mandibular first molars of 30 WT and 30 MyD88 KO mice. After 7, 21 and 42 days, the animals were euthanized and the mandibles were subjected to histotechnical processing. Histological sections were stained with haematoxylin and eosin (HE), TRAP histoenzymology,...
Authors: Raquel Assed Bezerra da Silva, Paulo Nelson-Filho, Marília Pacífico Lucisano, Andiara De Rossi, Alexandra Mussolino de Queiroz, Lea Assed Bezerra da Silva

Use of methodological tools for assessing the quality of studies in periodontology and implant dentistry: a systematic review

submitted by: Faggion
Objective To evaluate the methodological approaches used to assess the quality of studies included in systematic reviews (SRs) in periodontology and implant dentistry. Materials & Methods Two electronic databases (PubMed and Cochrane Database of Systematic Reviews) were searched independently to identify SRs examining interventions published through 2 September 2013. The reference lists of included SRs and records of 10 specialty dental journals were searched manually. Methodological...
Authors: Clovis Jr. Faggion, Fahd Huda, Jason Wasiak

Applying quality assurance in real-time to compliant long-term periodontal maintenance patients utilizing cost effectiveness and cost utility

submitted by: fardal
Background: Little work has been done on quality control of periodontal therapy Materials/methods: A quality control model was applied to 80 patients (50 females, 30 males) with an average age of 64.3 years (SD. 8.83, range 45-91) and with 21.6 (SD. 2.65, range 16-26) maintenance years. The main elements were patients’ expectations, objective and patient based outcomes, financial- and human costs and treatment deviations. Results: The patients’ main expectations and reasons for seeking...
Authors: Øystein Fardal

Soft tissue wound healing around teeth and dental implants

submitted by: zmkbern
Abstract Aim: To provide an overview on the biology and soft tissue wound healing around teeth and dental implants. Material and Methods: This narrative review focuses on cell biology and histology of soft tissue wounds around natural teeth and dental implants. Results and conclusions: The available data indicate that: (a) Oral wounds follow a similar pattern. (b) The tissue specificities of the gingival, alveolar and palatal mucosa appear to be innately and not necessarily functionally...
Authors: A Sculean, R Gruber, DD Bosshardt

Fundamental principles in periodontal plastic surgery and mucosal augmentation - a narrative review

submitted by: Rino
Aim: To provide a narrative review of the current literature elaborating on fun- damental principles of periodontal plastic surgical procedures. Methods: Based on a presumptive outline of the narrative review, MESH terms have been used to search the relevant literature electronically in the PubMed and Cochrane Collaboration databases. If possible, systematic reviews were included. The review is divided into three phases associated with periodontal plastic sur- gery: a) pre-operative...
Authors: Rino Burkhardt

Crevicular fluid biomarkers and periodontal disease progression

submitted by: Janet Kinney
AIM: Assess the ability of a panel of gingival crevicular fluid (GCF) biomarkers as predictors of periodontal disease progression (PDP). MATERIALS AND METHODS: 100 individuals participated in a 12-month longitudinal investigation and categorized into 4 groups according to their periodontal status. GCF, clinical parameters, and saliva were collected bi-monthly. Sub-gingival plaque and serum were collected bi-annually. For 6 months, no periodontal treatment was provided. At 6-months,...
Authors: Thomas Braun, William Giannobile, Janet Kinney, Thiago Morelli, Min Oh, Christoph Ramseier, James Sugai

Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.

submitted by: rumoreno
AIM: To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. METHODS: Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used...
Authors: Rubens Freitas

External cervical resorption: an analysis using cone beam and microfocus computed tomography and scanning electron microscopy

submitted by: Aske
Aim: To provide a three-dimensional representation of external cervical resorption (ECR) with microscopy, stereo microscopy, cone beam computed tomography (CT), microfocus CT and scanning electron microscopy (SEM). Summary: External cervical resorption is an aggressive form of root resorption, leading to a loss of dental hard tissues. This is due to clastic action, activated by a damage of the covering cementum and stimulated probably by infection. Clinically, it is a challenging...
Authors: V. Gunst, A. Mavridou, B. Huybrechts, G. Van Gorp, L. Bergmans, P. Lambrechts

Search strategies in systematic reviews in periodontology and implant dentistry

submitted by: Faggion
Objective: To perform an overview of literature search strategies in systematic reviews (SRs) published in periodontology and implant dentistry. Materials and Methods:Two electronic databases (PubMed and Cochrane Data- base of SRs) were searched, independently and in duplicate, for SRs with meta- analyses on interventions, with the last search performed on 11 November 2012. Manual searches of the reference lists of included SRs and 10 specialty dental jour- nals were conducted....
Authors: Clovis Faggion Jr., Momen Atieh, Stephanie Park

Disparity in embrasure fill and papilla height between tooth- and implant-borne fixed restorations in the anterior maxilla: a cross-sectional study

submitted by: jacosyn
Purpose: The objective of the present study was to compare interproximal fill and papilla height between different embrasures. Material and methods: One hundred and fifty non-smoking consecutive patients (mean age 54, range 32–73; 63 males and 87 females) without periodontal disease were selected in a multidisciplinary practice during regular supportive care. All had been treated for multiple tooth loss in the anterior maxilla at least one year earlier by means of a fixed restoration on...
Authors: Jan Cosyn, Hugo De Bruyn