biosights: August 6, 2012 - Redistribution aids the pore

submitted by: JCB
In animal cells, the nuclear lamina keeps nuclear pore complexes evenly distributed throughout the nuclear envelope. Steinberg et al. reveal that fungi, which lack nuclear laminae, prevent their nuclear pores from clustering by moving them around on cytoskeletal tracks, a process that also helps to organize fungal chromosomes and optimize nucleocytoplasmic transport. This biosights episode presents the paper by Steinberg et al. from the August 6, 2012, issue of The Journal of Cell Biology...

Cytoskeletal Motor Proteins by Ron Vale, July 2007 - Part 1: Introduction to Motor Proteins (43:13)

submitted by: video_collector
Molecular motor proteins are fascinating enzymes that power much of the movement performed by living organisms. In the first part of this lecture, I will provide an overview of the motors that move along cytoskeletal tracks (kinesin and dynein which move along microtubules and myosin which moves along actin). The main focus of this lecture is on how motor proteins work. How does a nanoscale protein convert energy from ATP hydrolysis into unidirectional motion and force production? What tools...