Genome-wide association study of chronic periodontitis in a general German population

submitted by: ateumer
Aim: To identify loci associated with chronic periodontitis through a genome wide association study (GWAS). Materials and Methods: A GWAS was performed in 4032 individuals of two independent cross-sectional studies of West Pomerania (SHIP n=3365 and SHIP-TREND n=667) with the different periodontal case definitions. Samples were genotyped with the Affymetrix Genome-Wide Human SNP Array 6.0 or the Illumina Human Omni 2.5 array. Imputation of the HapMap as well as the 1000 Genomes based...
Authors: A Teumer, B Holtfreter, U Völker, A Petersmann, M Nauck, R Biffar, H Völzke, HK Kroemer, P Meisel, G Homuth, T Kocher

All-cause mortality and periodontitis in 60–70-year-old men: a prospective cohort study

submitted by: Gerrylinden
Objective: To investigate the association between periodontitis and mortality from all causes in a prospective study in a homogenous group of 60-70 year-old Western European men. Methodology: A representative sample of 1400 dentate men, (mean age 63.8 SD 3.0 years), drawn from the population of Northern Ireland, had a comprehensive periodontal examination between 2001 and 2003. Men were divided into thirds on the basis of their mean periodontal attachment loss (PAL). The primary endpoint,...
Authors: Gerard Linden, Katie Linden, John Yarnell, Alun Evans, Frank Kee, Christopher Patterson