Genome-wide association study of chronic periodontitis in a general German population

submitted by: ateumer
Aim: To identify loci associated with chronic periodontitis through a genome wide association study (GWAS). Materials and Methods: A GWAS was performed in 4032 individuals of two independent cross-sectional studies of West Pomerania (SHIP n=3365 and SHIP-TREND n=667) with the different periodontal case definitions. Samples were genotyped with the Affymetrix Genome-Wide Human SNP Array 6.0 or the Illumina Human Omni 2.5 array. Imputation of the HapMap as well as the 1000 Genomes based...
Authors: A Teumer, B Holtfreter, U Völker, A Petersmann, M Nauck, R Biffar, H Völzke, HK Kroemer, P Meisel, G Homuth, T Kocher

Effect of periodontal disease on diabetes: systematic review of epidemiologic observational evidence

submitted by: WSB
Background: Periodontal disease and diabetes mellitus are common, chronic diseases worldwide. Epidemiologic and biologic evidence suggests periodontal disease may affect diabetes. Objective: To systematically review non-experimental, epidemiologic evidence for effects of periodontal disease on diabetes control, complications, and incidence. Data sources: Electronic bibliographic databases, supplemented by hand searches of recent and future issues of relevant journals. Study eligibility...
Authors: Wenche S. Borgnakke, Pekka V. Ylostalo, George W. Taylor, Robert R. Genco

Dr Escobedo discusses January 2010 Mayo Clinic Proceedings article

submitted by: mcgheekkm

Dr. Jorge Escobedo of the Mexican Social Security Institute, Mexico City, discusses January 10 Mayo Clinic Proceedings (http://tinyurl.com/yjemrap) article describing a cohort of patients selected for the presence of coronary artery disease, duration of diabetes mellitus of 20 or more years, and microalbuminuria or macroalbuminuria.