Exergaming and Older Adult Cognition: A Cluster Randomized Clinical Trial

submitted by: gowanc
Background: Dementia cases may reach 100 million by 2050. Interventions are sought to curb or prevent cognitive decline. Exercise yields cognitive benef?ts, but few older adults exercise. Virtual reality–enhanced exercise or “exergames” may elicit greater participation. Purpose: To test the following hypotheses: (1) stationary cycling with virtual reality tours (“cybercycle”) will enhance executive function and clinical status more than traditional exercise; (2) exercise...
Authors: Cay Anderson-Hanley, PhD, Paul Arciero

Genetic Contribution To Variation In Cognitive Function In Twins

submitted by: Koten

Genetic Contribution To Variation In Cognitive Function In Twins As Assessed With Functional MR Imaging.
This video shows that the brain activity patterns of MZ twins are more similar then brain activity patterns of siblings.

Cannabinoids

submitted by: alex01
Daniele Piomelli, PhD. - Another approach was discussed by D. Piomelli (University of California, Irvine). URB 597, an inhibitor of fatty acid amide hydrolase (FAAH), is expected to increase anandamide signaling and is being currently clinically tested in the therapy of pain. An increase in anandamide signaling may also be useful in the therapy of depression. This is a novel approach to the development of antidepressants. The signaling can be enhanced by blocking anadamide metabolism or by...

Methylphenidate Decreased the Amount of Glucose Needed by the Brain to Perform a Cognitive Task

submitted by: noravolkow
The use of stimulants (methylphenidate and amphetamine) as cognitive enhancers by the general public is increasing and is controversial. It is still unclear how they work or why they improve performance in some individuals but impair it in others. To test the hypothesis that stimulants enhance signal to noise ratio of neuronal activity and thereby reduce cerebral activity by increasing efficiency, we measured the effects of methylphenidate on brain glucose utilization in healthy adults. We...
Authors: Nora d. Volkow, Joanna s. Fowler, Gene-jack Wang, Frank Telang, Jean Logan, Christopher Wong, Jim Ma, Kith Pradhan, Helene Benveniste, James m. Swanson