Cell-Cell Communication in Bacteria by Bonnie Bassler, June 2008 - Part 1: Bacterial Quorum Sensing: Intra- and Inter-Species Communication (53:48)

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Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the...

Cell Organization & Cell Motility by Julie Theriot - Part 1: Cell Motility and the Cytoskeleton: Protein Polymers Crawling Cells and Comet Tails (43:53)

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This lecture covers the biochemical basis of actin-based motility (focusing on the pathogen Listeria as a model system for this process), the biophysical mechanism of polymerization-based force generation, and an evolutionary perspective of cell shape in prokaryotes and eukaryotes. The first part covers our understanding of how cells use the actin cytoskeleton to crawl. The pathogenic bacteria Listeria (which causes food poisoning) uses the actin cytoskeleton to propel itself in the...