Multiple myeloma is a cancer caused by malignant plasma cells. Plasma cells help the human body fight infection, but when they multiply out of control, the myeloma cells overpower the bone’s healthy cells causing harmful side effects; such as bone fractures and infections. Sheeba Thomas, M.D., assistant professor in Lymphoma/Myeloma at MD Anderson Cancer Center, discusses the basics, risk factors, diagnosis and treatment options for this rare cancer.

Background: Dairy product and calcium consumption have been associated with modifying body fat and body weight in children and adults. Objective: In overweight adolescent boys and girls, we aimed to determine the effect of the doubling of habitual calcium intake to the recommended intake from dairy or calcium carbonate on energy balance and purported mechanisms including fecal fat excretion, macronutrient use, and parathyroid hormone suppression. Design: Twenty-five girls with a mean...

Reconstructing Asian Monsoon History from Chinese Speleothems; Kathleen R. Johnson, Department of Earth System Science, University of California, Irvine: While we know that modern anthropogenic climate change is superimposed upon significant natural climate variability, the instrumental record of climate is too short to capture the full range of this variability. In order to fully understand and predict future changes, therefore, high-resolution, welldated paleoclimate records are needed to...

Dr. Catterall describes autoinhibitory control of cardiac L-type cardiac calcium channels by protein
phosphorylation and macromolecular signaling as well as regulation of P/Q type calcium currents in
neurons. His research suggests novel targets for drugs affecting cardiovascular or central nervous
systems.