Clinical Pearls in Men's Health.

submitted by: mcgheekkm

Dr. Beckman discusses his article appearing in the July 2010 issue of Mayo Clinic Proceedings commenting on three cases involving men's health.

Rethinking proteasome evolution: two novel bacterial proteasomes.

linked profile(s): Phil
submitted by: drnknmstrr
The proteasome is a multisubunit structure that degrades proteins. Protein degradation is an essential component of regulation because proteins can become misfolded, damaged, or unnecessary. Proteasomes and their homologues vary greatly in complexity: from HslV (heat shock locus v), which is encoded by 1 gene in bacteria, to the eukaryotic 20S proteasome, which is encoded by more than 14 genes. Despite this variation in complexity, all the proteasomes are composed of homologous subunits. We...
Authors: Valas Re, Bourne Pe