Foam cell formation is the hallmark of early atherosclerosis. Lipid uptake by scavenger receptors (SR) in macrophages
initiates chronic proinflammatory cascades linked to atherosclerosis. It has been reported that the upregulation of
cholesterol efflux may be protective in the development of atherosclerosis. Ellagic acid, a polyphenolic compound mostly
found in berries, walnuts, and pomegranates, possesses antioxidative, growth-inhibiting and apoptosis-promoting
activities in cancer...
Authors: Young-Hee Kang, Min-Kyung Kang, Ju-Hyun Gong, Seon-Young Han, Eun-Sook Lee, Jung-Lye Kim, Sin-Hye Park