Modern proteomes contain putative imprints of ancient shifts in trace metal geochemistry

submitted by: cdupont
Because of the rise in atmospheric oxygen 2.3 billion years ago (Gya) and the subsequent changes in oceanic redox state over the last 2.3–1 Gya, trace metal bioavailability in marine environments has changed dramatically. Although theorized to have influenced the biological usage of metals leaving discernable genomic signals, a thorough and quantitative test of this hypothesis has been lacking. Using structural bioinformatics and whole-genome sequences, the Fe-, Zn-, Mn-, and...
Authors: Christopher l. Dupont, Song Yang, Brian Palenik, Philip e. Bourne