Andrew S. Greene, Ph.D.

submitted by: MCW_BBC

Andrew S. Greene, Ph.D., Director of the Biotechnology and Bioengineering Center and a professor of Physiology at the Medical College of Wisconsin describes his research in proteomics.

Microtubules Keep Tumor Cells Breathing Easy

submitted by: JCB
The transcription factor HIF-1α is essential for a cell's response to low oxygen conditions. Carbonaro et al. demonstrate that production of HIF-1α protein is regulated by dynamic microtubules and that microtubule-targeting drugs shift HIF-1α mRNA into cytoplasmic P-bodies, where its translation is repressed by miRNAs. This biosights episode presents the paper by Carbonaro et al. from the January 10, 2011, issue of The Journal of Cell Biology, and includes an interview with authors Marisa...

Through The Eyes of a Child: Understanding Retinopathy through ROP (The Friedenwald Lecture)

submitted by: arvojenny
Retinopathy is a common cause of blindness in all age groups. There are 15 million people in the United States with age-related macular degeneration (AMD)—20% of those aged 65 to 74 years and 30% aged 74 years—and 1.6 million of those have neovascular (wet) AMD. In the working age population there are 20 million (7% of the population) with diabetes, and 50% of patients with diabetes mellitus have diabetic retinopathy (DR) after 25 years. In children, retinopathy of prematurity (ROP)...
Authors: Lois Smith

Dr. Shernan Holtan discusses November 9 Mayo Clinic Proceedings article on parallels between cancer and pregnancy

submitted by: mcgheekkm

Dr. Shernan Holtan, Instructor in Medicine and Oncology at Mayo Clinic, discusses her November 2009 Mayo Clinic Proceedings article on the parallels between cancer and pregnancy (article available at, particulary in terms of immunologic modulation.

AMPK and Akt crosstalk controls dura mater post ovariectomy microvascular remodeling in pigs

submitted by: glinskiio5766

Olga Glinskii shares her poster presentation at the Experimental Biology 2008 conference.