MICW - Scalability of Comparative Analysis, Novel Algorithms and Tools: Kostas Mavrommatis

submitted by: JGI

DOE JGI's Kostas Mavrommatis, chair of the Scalability of Comparative Analysis, Novel Algorithms and Tools panel, at the Metagenomics Informatics Challenges Workshop held at the DOE JGI on October 12-13, 2011.

Integrated Information System for Genomic and Metagenomic Data Analysis at National Center for Biotechnology Information (NCBI)

submitted by: dougramsey
Recent advances in biotechnology and bioinformatics has provided a flood of genomic data and tremendous growth in the number of associated data sets. Sequencing projects now include draft assemblies, complete genomes, comparative genomics, and metagenomics where genetic material is sequenced directly from environmental samples. The NCBI provides integrated systems for data storage, retrieval, and analysis. GenBank, an archival database of DNA sequences, contains consensus sequences assembled...

Comparative Metagenomics

submitted by: dougramsey
Each metagenome study of a complex habitat is accompanied by lots of unknowns as so far the depth of sequencing is usually insufficient to reveal the entire microbial community of an ecosystem. The probably easiest way of extracting meaningful information is the comparison with existing data, analogous to that of genome comparisons. However, the complexity within the analysis chain of a single metagenome annotation is topped by the difficulties that the integration of heterogeneously...