Organizing Principles for Amyloid Structure, Fibril Model, part 3; Competence in B. subtilis, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Daniel Cox (6:15)
Daniel Schultz (46:30)

Organizing Principles for Amyloid Structure, part 2; The Role of Noise in Small Genetic Networks, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Daniel Cox (0:00)
Daniel Schultz (45:49)

Energetic Frustration, Funnel Landscapes, and Topological Frustration, part 2; Organizing Principles for Amyloid Structure, part 1

submitted by: icamvid

Presented at the I2CAM/FAPERJ Spring School, 2008 in Rio de Janeiro, Brazil
Jos

Alzheimer's Disease

submitted by: alex01
Z. Khachaturian, PhD. - New approaches to the therapy of Alzheimer’s disease (AD) are discussed in video interviews of this series. According to Z. Khachaturian (Potomac, MD) substantial progress has been made during the last 10 years in our understanding of pathogenesis of Alzheimer’s disease as well as in the discovery of biomarkers and therapeutic approaches. In addition to cholinergic drugs, inhibitors of plaque formation have been discovered, but the currently available...

Bacterial Inclusion Bodies Contain Amyloid-Like Structure

linked profile(s): Lei Wang
submitted by: apryl
Protein aggregation is a process in which identical proteins self-associate into imperfectly ordered macroscopic entities. Such aggregates are generally classified as amorphous, lacking any long-range order, or highly ordered fibrils. Protein fibrils can be composed of native globular molecules, such as the hemoglobin molecules in sickle-cell fibrils, or can be reorganized β-sheet–rich aggregates, termed amyloid-like fibrils. Amyloid fibrils are associated with several...
Authors: David Eisenberg, Samir K Maji, Roland Riek, Michael R Sawaya, Lei Wang