JAMIA Webinar - 2013

submitted by: Jamia

March 2013, JAMIA Webinar. Presenter: Griffin Weber,MD. CIO of Harvard Medical School

Feb-2013 JAMIA Webinar (UCSD, Division of Biomedical Informatics)

submitted by: Jamia

Clinical Decision Support for Genetically Guided Personalized Medicine: a Systematic Review

Online Disease Management of Diabetes: (EMPOWER-D)

submitted by: Jamia
Full title: Online Disease Management of Diabetes: Engaging and Motivating Patients Online With Enhanced Resources-Diabetes (EMPOWER-D), A Randomized Controlled Trial Abstract: OBJECTIVE: To evaluate an online disease management system supporting patients with uncontrolled type 2 diabetes. MATERIALS AND METHODS: Engaging and Motivating Patients Online With Enhanced Resources for Diabetes was a 12-month parallel randomized controlled trial of 415 patients with type 2 diabetes with...

Identifying Clinical/Translational Research Cohorts: Ascertainment via Querying an Integrated Multi-Source Database

submitted by: Jamia
Abstract: BACKGROUND: Ascertainment of potential subjects has been a longstanding problem in clinical research. Various methods have been proposed, including using data in electronic health records. However, these methods typically suffer from scaling effects-some methods work well for large cohorts; others work for small cohorts only. OBJECTIVE: We propose a method that provides a simple identification of pre-research cohorts and relies on data available in most states in the USA: merged...

Patient Characteristics associated with Venous Thromboembolic Events: a Cohort Study Using Pooled Electronic Health Record Data

submitted by: Jamia
Abstract: Objective: To demonstrate the potential of de-identified clinical data from multiple healthcare systems using different electronic health records (EHR) to be efficiently used for very large retrospective cohort studies. Materials and methods: Data of 959,030 patients, pooled from multiple different healthcare systems with distinct EHR, were obtained. Data were standardized and normalized using common ontologies, searchable through a HIPAA-complaint, patient de-identified web...

Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy...

submitted by: Jamia
Full title: Deriving rules and assertions from pharmacogenomics knowledge resources in support of patient drug metabolism efficacy predictions Abstract: Objective Pharmacogenomics evaluations of variability in drug metabolic processes may be useful for making individual drug response predictions. We present an approach to deriving ‘phenotype scores’ based on existing pharmacogenomics knowledge and a patient's genomics data. Pharmacogenomics plays an important role in the bioactivation...

AMIA Board White Paper on Biomedical Informatics Definition and Core Competencies

submitted by: Jamia
Abstract The AMIA biomedical informatics (BMI) core competencies have been designed to support and guide graduate education in BMI, the core scientific discipline underlying the breadth of the field's research, practice, and education. The core definition of BMI adopted by AMIA specifies that BMI is ‘the interdisciplinary field that studies and pursues the effective uses of biomedical data, information, and knowledge for scientific inquiry, problem solving and decision making, motivated...

Probability of an Algorithm to Identify Rheumatoid Arthritis in Electronic Health Records

submitted by: Jamia
Abstract Objectives: Electronic health record (EHR) can allow for the generation of large cohort of individuals with given diseases for clinical and genomic research. A rate-limiting step is the development of electronic phenotype selection algorithms to find such cohorts. This study evaluated the portability of a published phenotype algorithm to identify rheumatoid arthritis (RA) patients from HER records at three institutions with different EHR systems. Material and Methods: Physicians...