Systematic Analysis of Human 5’UTR Introns Reveals Their Importance in Expression

submitted by: cancenik

Here, we describe a genome-scale computational analysis of 5’UTR introns in humans.

Epigenomics of Cancer - Prof. Wei Li (Part 1, 2009)

submitted by: ralanharris

Prof. Wei Li lectures on studies of transcription factor binding sites and histone modifications using ChIP-chip and Chip-seq assays. Part of the Computer Aided Discovery Methods 2009 course offered at Baylor College of Medicine.

A General Definition and Nomenclature for Alternative Splicing Events

submitted by: micha
Understanding the molecular mechanisms responsible for the regulation of the transcriptome present in eukaryotic cells is one of the most challenging tasks in the postgenomic era. In this regard, alternative splicing (AS) is a key phenomenon contributing to the production of different mature transcripts from the same primary RNA sequence. As a plethora of different transcript forms is available in databases, a first step to uncover the biology that drives AS is to identify the different...
Authors: Michael Sammeth, Sylvain Foissac, Roderic Guigó