Benoit Roux gives a talk at the RPP08 conference about free energy landscape, conformational changes and the transduction of biological signals. He also talks about the multiscale approaches to the activation, inactivation of Src kinases.
Carol Post gives a talk at the RPP08 conference on Src, a mechanism of conformational activation. She covers two topics regarding it Src:
1) Switched electrostatic network
2) long-range coupling of regulatory SH2/SH3 and catalytic domain