Inflammatory Bowel Disease: Perioperative Pharmacologic Considerations

submitted by: mcgheekkm

Description: Dr. Ajay Kumar, from the Department of Hospital Medicine at the Cleveland Clinic in Cleveland, Ohio, discusses his article on inflammatory bowel disease which appears in the August 2011 issue of Mayo Clinic Proceedings. Available at: http://www.mayoclinicproceedings.com/content/86/8/748.abstract

Treatment of Epilepsy

submitted by: alex01
Michael Rogawski (University of California, Davis) summarizes his research on the antiepileptic activity of neurosteroids (e.g. ganaxolone, allopregnanolone). They are allosteric modulators of GABAA receptors and are active in many models of epilepsy. They are expected, however, to be most effective in catamenial epilepsy, infantile spasms or adult partial seizures. National Institutes of Health (NIH) is currently sponsoring a clinical trial of progesterone (precursor of allopregnanolone)...