The Problem of Regeneration - Part 1: A Brief (Natural) History of Regeneration (32:38)

Regeneration has fascinated philosophers and scientists since the beginning of history. The wide but uneven... » More

Regeneration has fascinated philosophers and scientists since the beginning of history. The wide but uneven distribution of regenerative capacities among multicellular organisms is puzzling, and the permissive/inhibitory mechanisms regulating this attribute in animals remain a mystery. In the first part of this lecture, I will provide a general history of regeneration research from ancient Greece to the beginning of the 20th century. Key concepts will be introduced in their appropriate historical context, and many of the unanswered questions put forward by the problem of regeneration will be discussed. Planarians have attracted the attention of generations of biologists. It is not hard to see why: cut a worm into two fragments and each fragment regenerates a complete organism. Cut it into 8 fragments and each individual fragment will go on to regenerate a complete animal.

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