http://www.scivee.tv/PLOS_Pathogens en http://www.scivee.tv/pubcast/17397261 <p>CD8+ cytotoxic T-lymphocytes (CTLs) perform a critical role in the immune control of viral infections, including those caused by human immunodeficiency virus type 1 (HIV-1) and hepatitis C virus (HCV). As a result, genetic variation at CTL epitopes is strongly influenced by host-specific selection for either escape from the immune response, or reversion due to the replicative costs of escape mutations in the absence of CTL recognition.</p> <div class="og_rss_groups"><ul class="links"><li class="first last og_links"><a href="/PLOS_Pathogens" class="og_links">PLoS Pathogens</a></li> </ul></div><p><a href="http://www.scivee.tv/pubcast/17397261">read more</a></p> adaptation, biological cd8-positive t-lymphocytes epitopes, t-lymphocyte hepacivirus hepatitis c hiv infections hiv-1 humans models, biological models, theoretical molecular sequence data polymorphism, genetic reverse transcriptase p PLoS Pathogens Fri, 21 Sep 2007 14:12:02 -0700 art 2755 at http://www.scivee.tv