I have attached a word doc and pasted below some ideas we came up with today.
Project Ideas
- Extensions to current protocols in the GFP and Protein purification lab
- Infecting bacterial cells with virus and looking at different factors that effect uptake of GFP
- Sorting Genes that are anti-biotic resistance based on transformation
- Determining which genes confer anti-biotic resistance to bacterial cells
- We will refine our ideas more when we work with the Science teacher
Scientist
- Share his research and how he might prevent HIV infection and how this research is similar to what happens in his lab
- Provide a timeline or historical overview of related science.
Media
- Creating diagrams or illustrations showing what is happening on the cellular level
- Create animations showing the interaction of proteins in cells
- Show / illustrate how a FACS machine works
- Create vids documenting the process or showing the end result.
- A video game showing cellular growth or process
Authentic Audience
- SIA website
- San Diego Science Festival
- Present at the school science fair
- Create an academy presentation event
- Share with HSP students maybe a Peer review
- Set up at an AIDS walk or similar event
Discipline Integration
- Probability and statistics with the DNA
- Conversion of units of measure
- Geometric structure of viruses
- Describe / write about how these viruses affect humans
- Write (functional writing) describing the scientific process used in the project
- Embedding literary elements using a fictional novel about HIV (or disease)
RNA interference (RNAi) and protein knockouts are also current, relevant and interesting to students. Kelly, an undergrad at UCSD, is currently working on a protocol developed by Lindsay: RNAi in C. elegans in promoting a DPY-10 phenotype. Her goal is to make it available through the Biobridge network. Just a thought! DK