Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)

January 8, 2010
DOI: 10.4016/15544.01
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Conference:
Translational Proteomics 2.0 Meeting (hosted by Sage-N Research)
Key findings:
Semi-enzymatic searches with a target-decoy search methodology allows accurate false discovery rate estimation.
Description:
How to improve signal-to-noise in proteomics search engine results from tandem mass spectrometry