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Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)
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DOI: 10.4016/15544.01
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Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)
by:
dachian
|
January 8, 2010
Conference:
Translational Proteomics 2.0 Meeting (hosted by Sage-N Research)
Key findings:
Semi-enzymatic searches with a target-decoy search methodology allows accurate false discovery rate estimation.
How to improve signal-to-noise in proteomics search engine results from tandem mass spectrometry
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mass spec
Mass Spectrometers
peptide MS data
peptide sequencing algorithms
PeptideProphet
protein identification
ProteinProphet
proteomics
Sage-N Research
Sequest
shotgun mass spectrometry
SORCERER
Subject areas
biochemistry
biotechnology
cell biology
information science
life science
molecular
protein