Addressing Peptide ID Signal-to-Noise with Target-Decoy Searching (Proteomics)
January 8, 2010
- Translational Proteomics 2.0 Meeting (hosted by Sage-N Research)
- Key findings:
- Semi-enzymatic searches with a target-decoy search methodology allows accurate false discovery rate estimation.
How to improve signal-to-noise in proteomics search engine results from tandem mass spectrometry