Journal of Nutrition

Oligosaccharide-Induced Whey-Specific CD25+ Regulatory T-Cells Are Involved in the Suppression of Cow Milk Allergy in Mice

Bastiaan — Tue, 16 Mar 2010 08:38:00 -0700

Dietary intervention with a unique prebiotic nondigestible carbohydrate mixture has been shown to reduce the development of allergic disease in infants at risk. In this study, the involvement of CD25+ regulatory T-cells (Treg) in the carbohydrate-induced effects was investigated in mice orally sensitized with whey using adoptive transfer experiments. Donor mice were sensitized with whey and fed a diet containing short-chain galacto-, long-chain fructo- and acidicoligosaccharides, or a control diet starting 2 wk before sensitization.

Journal of Nutrition

Cash and in-kind transfers in poor rural communities in Mexico increase household fruit, vegetable, and micronutrient consumption but also lead to excess energy consumption

jefleroy — Thu, 18 Feb 2010 09:51:56 -0800

Conditional transfer programs are increasingly popular, but the impact on household nutrient consumption has not been
studied. We evaluated the impact of the Programa de Apoyo Alimentario (PAL), a cash and in-kind transfer program, on the
energy and nutrient consumption of poor rural households in Mexico. The program has been shown to reduce poverty.
Beneficiary households received either a food basket (including micronutrient-fortified milk) or cash. A random sample of
206 rural communities in Southern Mexico was randomly assigned to 1 of 4 groups: a monthly food basket with or without

Journal of Nutrition

Acute Ingestion of Long-Chain (n-3) Polyunsaturated Fatty Acids Decreases Fibrinolysis in Men with Metabolic Syndrome

lrobinson — Wed, 06 Jan 2010 10:01:57 -0800

Individuals with metabolic syndrome (MetS) often have elevated plasma plasminogen activator inhibitor-1 (PAI-1) and
tissue plasminogen activator (t-PA), contributing to an increased risk of cardiovascular disease. PAI-1 and t-PA may be
affected by chronic (n-3) long-chain PUFA [(n-3)LCPUFA] supplementation; however, the acute impact of fat ingestion on
these risk factors has not been established. Our objective was to investigate the acute effect of (n-3)LCPUFA on plasma

Journal of Nutrition

Iron-Deficiency Sensitizes Mice to Acute Pain Stimuli and Formalin-Induced Nociception.

pdowling — Mon, 19 Oct 2009 08:31:36 -0700

Iron deficiency has been described as a risk factor in secondary restless legs syndrome (RLS), although it has not been investigated whether iron deficiency induces sensory symptoms in RLS patients. In this study, we established a mouse model of iron deficiency by administering a purified iron-deficient (ID) diet (<8 mg/kg iron) or nonpurified standard diet [normal diet (ND)] (<179 mg/kg iron) to male C57Bl/6 mice from postnatal d 28 for 1, 4, or 15 wk. The level of iron deficiency was assessed by the plasma iron concentration.