Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Leonard Zon Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Fri, 27 Feb 2009 07:59:07 -0800

Dr. Leonard Zon is internationally recognized for his pioneering work in the fields of stem cell biology and cancer genetics. He received his MD from Jefferson Medical College, Philadelphia. He is founder and former president of the International Society for Stem Cell Research and chair of the Executive Committee of the newly formed Harvard Stem Cell Institute (HSCI). In 2005, Dr. Zon was elected to the Institute of Medicine of the National Academies. He recently completed a term as President of the American Society for Clinical Investigation.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Richard Young Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Fri, 27 Feb 2009 07:26:02 -0800

Richard Young’s research combines novel high-throughput biological methods with new computational techniques to investigate the mechanisms that control genes in living cells. Recent results from his group include the discovery of the core regulatory circuitry of human embryonic stem cells and insights into the mechanisms that control human development. Dr. Young believes that knowledge of regulatory circuitry will provide the foundation for future therapeutic strategies against major human diseases.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Max S. Wicha Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Fri, 27 Feb 2009 06:50:12 -0800

Dr. Max S. Wicha is the founding Director of the University of Michigan Comprehensive Cancer Center and distinguished professor of oncology. His lab was part of the team that first discovered stem cells in breast cancer, the first described in any human solid tumor. He is a leading expert in normal and malignant breast stem cells. Dr. Wicha is also active as a clinician, specializing in the treatment of breast cancer.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Irving L. Weissman Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Fri, 27 Feb 2009 06:14:43 -0800

Irving L. Weissman, M.D., is the Director of the Stanford Institute for Stem Cell Biology and Regenerative Medicine, Director of the Stanford Cancer Center and Director of the Stanford Ludwig Center for Stem Cell Research. Dr. Weissman was a member of the founding Scientific Advisory Boards of Amgen (1981-1989), DNAX (1981-1992), and T-Cell Sciences (1988-1992). He co-founded SyStemix in 1988, StemCells in 1996, and Celtrans (now Cellerant), the successor to SyStemix, in 2001. He is a Director and Chair of their Scientific Advisory Boards.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Fiona Watt Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Fri, 27 Feb 2009 05:31:38 -0800

Fiona Watt obtained her undergraduate degree from Cambridge University and her DPhil from the University of Oxford. She was a postdoctoral fellow with Howard Green at MIT and it was there that she first studied mammalian epidermis. After running a lab in London for many years, she moved to Cambridge in 2007. She is deputy director of the Cancer Research UK Cambridge Research Institute and the Wellcome Trust Centre for Stem Cell Research.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Amy Wagers Interviewed by Richard Sever

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 13:40:11 -0800

Dr. Amy Wagers is an Investigator in the Section on Developmental and Stem Cell Biology at Joslin Diabetes Center as well as an Assistant Professor in the Department of Stem Cell and Regenerative Biology at Harvard University and a Principal Faculty member of the Harvard Stem Cell Institute. She received her doctoral degree in Immunology and Microbial Pathogenesis from Northwestern University, and completed postdoctoral fellowship training in the laboratory of Dr. Irving Weissman, M.D., at Stanford University School of Medicine.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Elly Tanaka Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 13:03:14 -0800

Elly Tanaka performed her doctoral work with Marc Kirschner in the Department of Biochemistry, UCSF until 1994. From there she went on to do post-doctoral research with Jeremy Brockes at the Ludwig Institute and University College London. In 1999 she started a junior research group at the Max-Planck Institute of Molecular Cell Boiology and Genetics, Dresden where she was promoted to associate level in 2004. In 2008 she was appointed Chair, Animal Models of Regeneration in the newly established Center for Regenerative Therapies, Dresden at the University of Technology, Dresden.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Azim Surani Interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 12:29:42 -0800

Azim Surani obtained his PhD in Mammalian Development at the University of Cambridge. He is the Marshall-Walton Professor at the Wellcome Trust/Cancer Research UK Gurdon Institute, University of Cambridge, since 1991, and a Professorial Fellow of King's College, Cambridge. He is an Associate Fellow of the Third World Academy of Sciences (1992), Fellow of the Academy of Medical Sciences (2001), a Member of EMBO (1993), and of Academia Europea (1994).

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Bruce Stillman Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 11:55:33 -0800

Dr. Bruce Stillman is President of Cold Spring Harbor Laboratory on the north shore of Long Island in New York. A native of Australia, he obtained a Bachelor of Science degree with honors at Sydney University and a Ph. D. at the John Curtin School of Medical Research at the Australian National University. He then moved to Cold Spring Harbor Laboratory as a Postdoctoral Fellow in 1979 and has been at the Laboratory ever since, being promoted to the scientific staff in 1981. Dr.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Allan Spradling Interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 11:34:53 -0800

Allan Spradling has contributed extensively to the technology of genetic manipulation in Drosophila melanogaster and applied these methods to fundamental problems of germ cell and stem cell development. With Gerry Rubin, he showed that transposable elements can function as transformation vectors, and used this approach to carry out the first successful gene therapy in a multicelluar organism.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Davor Solter interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 07:31:39 -0800

Davor Solter, M.D. (1965), Ph.D. (1971) both from the University of Zagreb, Croatia. Assistant and associate Professor in the Departments of Anatomy and Biology, University Zagreb Medical School 1966-1973. In 1973 moved to the Wistar Institute, Philadelphia and became Member and Professor in 1981 as well as Wistar Professor at the University of Pennsylvania. In 1991 he was appointed Member of the Max-Planck Society and Director of the Max-Planck Institute of Immunobiology in Freiburg. He is also Adjunct Professor at the Jackson Laboratory, Bar Harbor.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Ben Scheres Interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 06:47:45 -0800

Ben Scheres investigates Arabidopsis development at Utrecht University since 1990. His group exploits the root tip as a tractable model for stem cells. Initially, the group focused on mechanisms of pattern formation. More recently, cell division and cell polarity in plants have become separate research topics –the ultimate aim is to connect these intertwined processes and provide an explanation for maintenance and specialization of stem cell groups in plant growth regions.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Guy Sauvageau Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 06:03:01 -0800

Guy Sauvageau is the Founding Scientific Director of the Institute for Research in Immunology and Cancer (IRIC). He also holds the Canada Research Chair in the Molecular Genetics of Stem Cells and is Full Professor with the Université de Montréal Department of Medicine. Dr. Sauvageau is a researcher and clinical practitioner, specializing in the transplantation of bone marrow-derived stem cells, called hematopoietic stem cells, and in the study of the molecular mechanism involved in their self-renewal.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Steve Reiner Interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Thu, 26 Feb 2009 05:17:28 -0800

Steve Reiner received a B.A. in philosophy from Haverford College in 1982. He received an M.D. degree from Duke University in 1985. He is clinically trained in internal medicine and infectious diseases. He performed postdoctoral research at the University of California, San Francisco in the laboratory of Richard Locksley from 1990 to1994. In 1994, he took his first faculty appointment, in the Gwen Knapp Center for Lupus and Immunology Research at The University of Chicago.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Luis F. Parada Interviewed by Catherine Cormier,

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 15:04:22 -0800

Luis F. Parada grew up in Bogota, Colombia. He obtained a BS from the University of Wisconsin and a Ph.D. in Biology from MIT in 1985 identifying oncogenes in human cancer. He was a Damon Runyon and later Helen Hay Whitney Postdoctoral Fellow at the Pasteur Institute. From 1988 to 1994, he headed the Molecular Embryology Section at the NCI in Frederick, Maryland. His work there centered on the identification and characterization of Trk receptor tyrosine kinases as physiological neurotrophin receptors. In 1994 Dr.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Sean Morrison Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 13:30:51 -0800

Sean Morrison’s laboratory studies the cellular and molecular mechanisms that regulate stem cell function in the nervous and hematopoietic systems. Dr. Morrison obtained his B.Sc. in biology and chemistry from Dalhousie University (1991), then completed a Ph.D. in immunology at Stanford University (1996), and a postdoctoral fellowship in neurobiology at Caltech (1999). Since 1999, Dr. Morrison has been at the University of Michigan, where his laboratory studies the mechanisms that regulate stem cell self-renewal and stem cell aging, as well as the link between stem cell function and cancer.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Ron McKay Interviewed by Richard Sever

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 12:45:47 -0800

Ron McKay received a B.Sc. in 1971 and a Ph.D. in 1974 from University of Edinburgh, where he studied under the tutelage of Edwin Southern examining DNA organization and chromosome structure. He received postdoctoral training at University of Oxford working with Walter Bodmer examining restriction-fragment-length polymorphism (RFLPs). In 1978, he became a senior staff investigator at Cold Spring Harbor Laboratory concentrating on two areas: the interaction of SV40 T antigen with the specific binding site at the viral origin of replication and the molecular organization of the nervous system.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Ihor R. Lemischka Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 12:11:59 -0800

Dr. Ihor R. Lemischka is currently the Director of the Black Family Stem Cell Institute, and Lillian and Henry M. Stratton Professor of Gene and Cell Medicine at the Mount Sinai School of Medicine in New York City. Dr. Lemischka relocated to Mount Sinai in July of 2007 after twenty-one years as Professor of Molecular Biology at Princeton University. Dr. Lemischka received his PhD from the Massachusetts Institute of Technology (MIT) in 1982 under the mentorship of Dr. Philip A. Sharp. He did his post-doctoral training with Dr. Richard C. Mulligan at the Whitehead Institute at MIT. In 1986 Dr.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Ruth Lehmann Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 10:53:41 -0800

Born in Cologne, Germany, Ruth Lehmann studied Drosophila embryology and genetics with Gerold Schubiger’s at the University of Washington, Seattle and with the late Jose Campos-Ortega at the University of Freiburg, Germany, where she described the neurogenic genes in Drosophila. During her doctoral thesis in the laboratory of Christiane Nuesslein-Volhard at the Max Planck Institute in Tuebingen, Germany, she characterized maternal effect genes that organize the embryonic axes in Drosophila.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Brigid Hogan Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 10:12:00 -0800

Brigid Hogan, PhD, FRS is the George Barth Geller Professor and Chair of the Department of Cell Biology, Duke University Medical Center. She is also Director of the Duke Stem Cell Program. Prior to joining Duke, Dr Hogan was an Investigator of the Howard Hughes Medical Institute and Hortense B. Ingram Professor in the Department of Cell Biology at Vanderbilt University Medical Center. Dr. Hogan earned her PhD in Biochemistry at the University of Cambridge. After completing her PhD, she was a postdoctoral fellow in the Department of Biology at MIT.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Arturo Alvarez-Buylla Interviewed by Jane Alfred

Cold Spring Harbor Laboratory — Wed, 25 Feb 2009 08:16:40 -0800

Arturo Alvarez-Buylla is the Heather and Melanie Muss Endowed Chair in the Department of Neurological Surgery and Professor of the Institute for Regeneration Medicine, University of California, San Francisco (UCSF). He received his undergraduate degree from National Autonomous University of Mexico (UNAM). In 1988 he obtained his PhD from Rockefeller University and after a brief postdoctoral fellowship, becomes Assistant Professor and then Associate Processor-Head of Laboratory at this same Institution. Since 2000, he is at UCSF. His early PhD and postdoctoral work in the laboratory of Dr.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Carla Kim Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Tue, 24 Feb 2009 14:16:56 -0800

Carla Kim received her PhD in Genetics from the University of Wisconsin-Madison and completed postdoctoral training at the Massachusetts Institute of Technology. She currently serves as an Assistant Professor in the Stem Cell Program at Children's Hospital in Boston and the Genetics Department at Harvard Medical School. She is a member of the Harvard Stem Cell Institute and the Dana-Farber Harvard Cancer Center. Dr. Kim developed a method to isolate the first stem cell population from the adult murine lung, termed bronchioalveolar stem cells (BASCs).

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Rudolf Jaenisch Interviewed by Richard Sever

Cold Spring Harbor Laboratory — Tue, 24 Feb 2009 13:11:31 -0800

Rudolf Jaenisch received his M.D. in Munich in 1967. After postdoctoral work at Princeton and five years as a Research Professor at the Salk Institute, he became Head of the Department of Tumor Virology at the Heinrich Pette Institute for Experimental Virology and Immunology. Since 1984 he has been a Founding Member of the Whitehead Institute and Professor of Biology at M.I.T. and in 2005 he established the Human Stem Cell Facility at the Whitehead.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Konrad Hochedlinger Interviewed by Jan Witkowski

Cold Spring Harbor Laboratory — Tue, 24 Feb 2009 07:29:06 -0800

Konrad Hochedlinger is an Assistant Professor of Medicine at Harvard Medical School, a Principal Faculty at the Harvard Stem Cell Institute and an Investigator at the Cancer Center and Center for Regenerative Medicine at the Massachusetts General Hospital. He received his B.Sc. in biology and his Ph.D. in genetics from the University of Vienna. From 1998-1999, he worked with Erwin Wagner at the Research Institute of Molecular Pathology in Vienna and from 2000-2003 as a Visiting Graduate Student and Boehringer Ingelheim Fonds-Fellow with Rudolf Jaenisch at the Whitehead Institute/MIT.

Control and Regulation of Stem Cells

Control and Regulation of Stem Cells with Alejandro Sánchez Alvarado Interviewed by Catherine Cormier

Cold Spring Harbor Laboratory — Fri, 30 Jan 2009 06:43:05 -0800

Born in Caracas Venezuela, February 24, 1964, Alejandro Sánchez Alvarado received his Bachelor’s Degree in Molecular Biology and Chemistry from Vanderbilt University in 1986. In 1992, he received his Ph.D. in Pharmacology and Cell Biophysics at the University of Cincinnati School of Medicine, where he studied mouse ES cells and their in vitro differentiation under the tutelage of Dr. Jeffrey Robbins and Thomas Doetschman. In 1994, he joined the laboratory of Dr. Donald D.