Pubcasts in Institution 2009
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Cdc42 controls spindle orientation to position the apical surface during epithelial morphogenesis
The establishment of apical–basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial morphogenesis. To examine the underlying mechanisms, the human...
The establishment of apical–basal polarity within a single cell and throughout a growing tissue is a key feature of epithelial morphogenesis. To examine the underlying mechanisms, the human...
2841 views since Apr 22, 2009
submitted by: JCB
Collective cell migration requires vesicular trafficking for chemoattractant delivery at the trailing edge
Chemoattractant signaling induces the polarization and directed movement of cells secondary to the activation of multiple effector pathways. In addition, chemotactic signals can be amplified and...
Chemoattractant signaling induces the polarization and directed movement of cells secondary to the activation of multiple effector pathways. In addition, chemotactic signals can be amplified and...
4952 views since Apr 22, 2009
submitted by: JCB
One-Dimensional Topography Underlies Three-Dimensional Fibrillar Cell Migration
Current concepts of cell migration were established in regular two-dimensional (2D) cell culture, but the roles of topography are poorly understood for cells migrating in an oriented 3D fibrillar...
Current concepts of cell migration were established in regular two-dimensional (2D) cell culture, but the roles of topography are poorly understood for cells migrating in an oriented 3D fibrillar...
2962 views since Apr 22, 2009
submitted by: JCB