iBioseminars

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Description: Modern biology is advancing at a staggering pace, and it is critical for students and researchers from the US and around the world, at small and large universities, to have access to outstanding seminars describing exciting advances in biology. However, many institutions have difficulty in attracting top scientists for their seminar series, due to a lack of travel funds as well as the limited travel time of speakers. Thus, there is a need for worldwide access to lectures by leading scientists.
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Human COPII genes are duplicated and some may have evolved specialized functions. Two rare human diseases affect the activity of one of two copies of Sar1 and the Sec23A subunit of the COPII coat. Anderson's disease results in the failure of enterocytes of the absorptive epithelium to secrete...

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Secretion mutants that block protein exit from the endoplasmic reticulum define genes involved in the formation, targeting and fusion of a small vesicle intermediate. SEC genes corresponding to the mutants defective in vesicle budding define the cytoplasmic machinery responsible for transport...

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In the second segment of my talk, I describe our work on cell number control in the rat oligodendrocyte cell lineage. Cell numbers depend on controls on both cell death and cell proliferation. We have found that oligodendrocytes are normally overproduced and kill themselves in large numbers in a...