The methodologies used to generate genome and metagenome annotations are diverse and vary between groups and laboratories. Descriptions of the... » More

The methodologies used to generate genome and metagenome annotations are diverse and vary between groups and laboratories. Descriptions of the annotation process are helpful in interpreting genome annotation data. Some groups have produced Standard Operating Procedures (SOPs) that describe the annotation process, but standards are lacking for structure and content of these descriptions. A general structure for SOP documents that are relevant to genome annotation, metagenomics, environmental samples and clinical samples will be presented. In addition, a proposal for a central repository to store and disseminate procedures and protocols for genome annotation will be discussed.

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