Making Muscle: Tissue Engineering in MUSC's Department of Surgery

submitted by: mcgheek
Samir Fakhry, M.D., Chief of MUSC's Division of General Surgery, and Michael Yost, PhD, Associate Chair of Research in MUSC's Department of Surgery, discuss the promise of engineered tissues for the treatment of surgical and trauma patients. Engineered tissue can instruct the body to regenerate native tissue instead of generating scar, improving cosmetic and functional outcomes. Bioprinters, 3D printers for living tissue, will help realize the promise of engineered tissue for clinical care.k

Soft tissue wound healing around teeth and dental implants

submitted by: zmkbern
Abstract Aim: To provide an overview on the biology and soft tissue wound healing around teeth and dental implants. Material and Methods: This narrative review focuses on cell biology and histology of soft tissue wounds around natural teeth and dental implants. Results and conclusions: The available data indicate that: (a) Oral wounds follow a similar pattern. (b) The tissue specificities of the gingival, alveolar and palatal mucosa appear to be innately and not necessarily functionally...
Authors: A Sculean, R Gruber, DD Bosshardt

Breast reconstruction rates rising after mastectomy

submitted by: mdanderson
New research shows most women receiving a mastectomy for breast cancer also have breast reconstruction. In 2007, 63% of patients received breast reconstruction, up from 46% in 1998. The new study shows women receiving radiation are less likely to get reconstruction; there are geographic variations for those undergoing the procedures; and more women are getting implants rather than using tissue from other parts of their bodies. Senior author Benjamin Smith, M.D., associate professor in...

Novel cell-based and materials science approach to target Glioblastoma brain cancer tumors

submitted by: nsf

Stefan Bossmann and Deryl Troyer at Kansas State University are developing a novel materials treatment method for persons with brain cancer that uses a type of white blood cell to deliver anticancer drugs to particularly virulent brain tumors.

Fundamental principles in periodontal plastic surgery and mucosal augmentation - a narrative review

submitted by: Rino
Aim: To provide a narrative review of the current literature elaborating on fun- damental principles of periodontal plastic surgical procedures. Methods: Based on a presumptive outline of the narrative review, MESH terms have been used to search the relevant literature electronically in the PubMed and Cochrane Collaboration databases. If possible, systematic reviews were included. The review is divided into three phases associated with periodontal plastic sur- gery: a) pre-operative...
Authors: Rino Burkhardt

Extraction sockets: erratic healing impeding factors

submitted by: freetist
Aim: The aim of this exploratory study was to analyse prevalence of extraction sockets showing erratic healing and evaluate factors potentially impeding healing. Methods: Erratic healing was defined as extraction sites showing clinical observations of fibrous scar tissue occupying the extraction site rather than bone following 12 or more weeks of healing. Computerized tomography was used to evaluate characteristics and calculate Hounsfield unit scores for sites showing erratic healing....
Authors: Jung-Hoon Kim, Cristiano Susin, Jeong-Hyun Min, Hee-Yeon Suh, Eun-Jung Sang, Young Ku, Ulf M. E. Wikesjo, Ki-Tae Koo