Cytoskeletal Motor Proteins: Part 2: Single Molecule Approaches for Understanding Molecular Motors (25:20)

submitted by: scivee-team

In the second part of this lecture, I will discuss our laboratories current work on the mechanism of movement by dynein, a motor protein about which we still know very little. This is a research story in progress, where some advances have been made. However, much remains to be done in order to understand how this motor works.

Cell Organization & Cell Motility: Part 3: Principles of Cellular Organization: The Universal Cytoskeleton (29:17)

submitted by: scivee-team
In the third part, I discuss how the complex shapes of cells are created by the cytoskeleton, and I compare and contrast prokaryotes (which have actin-, tubulin-, and intermediate filament -like proteins) and eukaryotes in this regard. In particular, I speculate that cytoskeletal dynamics were necessary to evolve simple bacterial shapes and cell division, but that additional layers of complexity (namely regulated nucleation and molecular motors) allowed eukaryotes to evolve more complex...

Cell Organization & Cell Motility: Part 2: Force Generation by Actin Assembly: Theories and Experiments (46:16)

submitted by: scivee-team

The second part is devoted to understanding how the polymerization of actin can produce, which is a current area of research in our laboratory. Here, I cover theories for how polymerization might be used to produce forces, and our efforts to test these models using optical traps, atomic force microscopes, and nanofabricated devices.

Targeted Human Genome Resequencing

submitted by: dougramsey

Targeted Human Genome Resequencing presented by Hanlee Ji, Stanford University Medical Center

Mapping the Arabidopsis Epigenome and Transcriptome by Deep Sequencing

submitted by: dougramsey

Mapping the Arabidopsis Epigenome and Transcriptome by Deep Sequencing presented by Ryan Lister

Informatics and Experimental Strategies for De Novo Genome Sequencing with Short Read

submitted by: dougramsey

Informatics and Experimental Strategies for De Novo Genome Sequencing with Short Reads presented by Elliott Margulies, National Human Genome Research Institute