Developmental Biology of a Simple Organism: Part 3: Stochasticity and Cell Fate (25:03)

submitted by: scivee-team

Part III presents research showing that B. subtilis uses a bet hedging strategy for coping with uncertainty.

Developmental Biology of a Simple Organism: Part 2: New Research on Multicellularity (18:13)

submitted by: scivee-team

Part II presents research on the capacity of B. subtilis cells to form architecturally complex communities.

Sex and Smell: Molecular Biology of Pheromone Perception: Part 3: Sex-Specificity of Pheromone Responses (30:39)

submitted by: scivee-team

Pheromones have evolved to signal the sex and the dominance status of animals and to promote social and mating rituals. In this lecture, I discuss the how pheromone sensing operates in mammals. I will discuss the molecular biology of the chemosensory receptors that are involved the first steps of pheromone sensing. At a higher level of complexity, I will discuss a distinct olfactory structure called the vomeronasal organ (VNO) and how it contributes to sex-specific behavioral responses.

Sex and Smell: Part 2: Molecular Biology of Pheromone Perception (43:43)

submitted by: scivee-team

Pheromones have evolved to signal the sex and the dominance status of animals and to promote social and mating rituals. In this lecture, I discuss the how pheromone sensing operates in mammals. I will discuss the molecular biology of the chemosensory receptors that are involved the first steps of pheromone sensing. At a higher level of complexity, I will discuss a distinct olfactory structure called the vomeronasal organ (VNO) and how it contributes to sex-specific behavioral responses.

Cell-Cell Communication in Bacteria: Part 2: Vibrio Cholerae Quorum Sensing and Developing Novel Antibiotics (19:49)

submitted by: scivee-team
Bacteria, primitive single-celled organisms, communicate with chemical languages that allow them to synchronize their behavior and thereby act as enormous multi-cellular organisms. This process is called quorum sensing and it enables bacteria to successfully infect and cause disease in plants, animals, and humans. Investigations of the molecular mechanisms underlying quorum sensing are leading to the development of novel strategies to interfere with quorum sensing. These strategies form the...

Cytoskeletal Motor Proteins: Part 3: Mining the Genome for Mitotic Treasures (33:41)

submitted by: scivee-team
The third (last) part of the lecture is on mitosis, the process by which chromosomes are aligned and then segregated during cell division. I will describe our efforts to find new proteins that are important for mitosis through a high throughput RNAi screen. I will discuss how we technically executed the screen and then focus on new proteins that are we discovered that are involved in generating the microtubules that compose the mitotic spindle. I also discuss the medical importance of...