Biomedical nomenclature is a valuable and ever-expanding tool that researchers can use in order to more easily learn about, refer to or retrieve any particular parts of the genome using the literature or through the use of curated data and a variety of tools, such as the ones available in RGD. This video showcases both QTL and marker nomenclature. For a copy of RGNC’s complete set of rules on nomenclature, visit: http://rgd.mcw.edu/nomen/nomen.shtml Or contact us at:...

This video focuses on rat gene nomenclature, noting how it is formed and where you can go to seek help when naming your genes. Biomedical nomenclature is a valuable and ever-expanding tool that researchers can use in order to more reliably retrieve data on any particular part of the genome through analysis tools, such as the ones available in RGD. Learn more about this vital mechanism. For a copy of RGNC’s complete set of rules on nomenclature, visit:...

Activated T cell receptors stimulate actin polymerization at the periphery of the immunological synapses that form between lymphocytes and antigen-presenting cells. Babich et al. reveal that the retrograde flow of actin, largely driven by continuous polymerization, is required to sustain downstream signaling events and T cell activation. This biosights episode presents the paper by Babich et al. from the June 11, 2012 issue of The Journal of Cell Biology and includes an interview with senior...

How to study the coagulation cascade

How to grow / culture yeast on agar or in YPD:

We show you how to prepare fresh cultures of yeast from previously grown agar plates.

Spruce up your old yeast cultures by replating onto fresh media or liquid YPD, or select colonies of interest to be expanded.

Full Yeast Protocol

Fibroblasts moving across two-dimensional surfaces form lamellipodial protrusions at their leading edge, but how cells move through three-dimensional environments is less well understood. Petrie et al. reveal that, depending on the strength of intracellular RhoA signaling and on the elastic properties of the extracellular matrix, fibroblasts can migrate through 3D environments using either lamellipodia or blunt, cylindrical protrusions called lobopodia. This biosights episode presents the...