Dynamic Remodeling of Individual Nucleosomes Across a Eukaryotic Genome in Response to Transcriptional Perturbation

submitted by: akshayb
The eukaryotic genome is packaged as chromatin with nucleosomes comprising its basic structural unit, but the detailed structure of chromatin and its dynamic remodeling in terms of individual nucleosome positions has not been completely defined experimentally for any genome. We used ultra-high–throughput sequencing to map the remodeling of individual nucleosomes throughout the yeast genome before and after a physiological perturbation that causes genome-wide transcriptional changes....
Authors: Sushma Shivaswamy, Akshay Bhinge, Yongjun Zhao, Steven Jones, Martin Hirst, Vishwanath r Iyer

MELANOMA THERMOGRAPHY

submitted by: camdic

Thermography allows the investigator to create a 3 dimensional image based on infrared emissions from tissue. Warmer tissues show up as yellow and white, whereas darker colors represent cooler structures. Malignant tumors are metabolically active and appear yellow and white on the images.
Metastatic melanoma in left inguinal lymphonodes - metastatic melanoma in left leg -
Prof. Camillo O. Di Cicco, MD

MITOCHONDRIAL DNA LAUNOIS-BENSAUDE's LIPOMATOSIS

submitted by: camdic
Even though Brodie is said to have first described diffuse symmetrical lipomatosis with predilection for the neck already in the 1846 (Clinical Lectures on Surgery, Delivered at St. George's Hospital Philadelphia: Lea and Blanchard pub. Pp 201-201. Brodie, B.C.) still unknown is today the pathogenesis of Launois Bensaude' Lipomatosis. Klopstock et Al. are found in muscle biopsy specimens ragged and red fibers, pathologic subsarcolemmal accumulations of mitochondria, suggesting a...

BEMuSE - protein folding for the grid

submitted by: iSGTW

This video is courtesy of EU-IndiaGrid and shows the setup of a simple simulation using BEMuSE, software for faster folding of proteins using grid computing. (http://euindia.ictp.it/bemuse/video-tutorials/)

This video shows:

* The structure of the restarts
* The configuration of a simulation
* The submission of the jobs

Installing and using the BioBar toolbar for Firefox

submitted by: simont

This video shows how to install and use the BioBar toolbar on Firefox. This is a nifty addition to the browser that makes accessing many of the usual online databases and tools very easy. It also allows you to easily run a search at these databases without having to navigate to the website first. BioBar can be found at biobar.mozdev.org and was written by Jawahar Swaminathan at the EBI.

Rosetta via GENIUS on the EUChinaGRID

submitted by: iSGTW

This video was produced by GILDA and INFN to show the use of Rosetta protein-folding software on the EUChinaGRID cyberinfrastructure via the GENIUS grid portal.