submitted by: Jaime Aguirre
In a flight of imagination to the beginning of the universe submerge your mind in the vastness of the newly formed space. Imagine you can see the constituents of the first atoms: electrons, protons, and neutrons. Now imagine the first atom as an electron surrounding a proton: hydrogen has been created…Add a second proton and two neutrons to the hydrogen nucleus, then add another electron around it, and helium is formed…And as the daydream continues the next element can be created by the...


submitted by: Jaime Aguirre
When Newlands made an analogy between his Law of Octaves and the musical scale he was ridiculed by the members of the English Chemical Society, and his paper describing this law was rejected. But Newlands was not so incongruent. Seeking musical patterns in natural phenomena has been a frequent endeavor throughout history. The Greek philosopher and mathematician Pythagoras of Samos argued that celestial bodies in rotation gave off pitched sounds that blended into a cosmic harmony, which he...

Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis

submitted by: arup.indra
Keratinocytes contribute to melanocyte activity by influencing their microenvironment, in part, through secretion of paracrine factors. Here we discovered that p53 directly regulates Edn1 expression in epidermal keratinocytes and controls UV-induced melanocyte homeostasis. Selective ablation of EDN1 in murine epidermis (EDN1ep-/-) does not alter melanocyte homeostasis in newborn skin but decreases dermal melanocytes in adult skin. Results showed that keratinocytic EDN1 in a non-cell...
Authors: Daniel J. Coleman, Gitali Ganguli-Indra, Stephen Hyter, Arup Indra, Steven Ma, Gary F. Merrill, Masashi Yanagisawa

Multivitamin-multimineral supplementation and mortality: A meta-analysis of randomized controlled trials

submitted by: mpase
Background: Multivitamins are the most commonly used supplement in the developed world. Recent epidemiological findings suggest multivitamin use increases the risk of mortality. Objectives: We aimed to determine whether multivitamin-multimineral treatment, used for primary or secondary prevention, increases the risk of mortality in independently living adults. Methods: We performed a meta-analysis of randomized, controlled trials. Multiple electronic databases were systematically searched...
Authors: Helen Macpherson, Andrew Pipingas, Matthew Pase

Biophysical Chemist - Profiles of Scientists and Engineers

submitted by: nsf

What's it really like to be an engineer or a scientist? What do they really do all day? You're about to find out! Meet the next generation of engineers and scientists in these profiles of young professionals, who may just inspire you to join them. Rommie Amaro tells us what it's like to be a biophysical chemist.

Metronidazole alone or with amoxicillin as adjuncts to non-surgical treatment of chronic periodontitis: a 1-year double-blinded, placebo-controlled, randomized clinical trial.

submitted by: mferes
AIM: To evaluate the effects of the adjunctive use of metronidazole (MTZ) or MTZ + amoxicillin (AMX) in the treatment of generalized chronic periodontitis (ChP). A secondary aim was to examine a possible added effect of chlorhexidine to these therapies. METHODS: One hundred and eighteen subjects received scaling and root planing (SRP) only or with MTZ [400 mg/thrice a day (TID)] or MTZ+AMX (500 mg/TID) for 14 days. Half of the subjects in each group rinsed with 0.12% chlorhexidine twice a...
Authors: Magda Feres