The position of the mitotic spindle is controlled by the microtubule-based motor dynein and a ternary complex of the proteins NuMA, LGN, and Ga. Kotak et al. demonstrate that the ternary complex's primary function is to localize dynein to the cell cortex and that cortical dynein is sufficient to position the mitotic spindle in HeLa cells. This biosights episode presents the paper by Kotak et al. from the October 1, 2012, issue of The Journal of Cell Biology and includes an interview with...

This video was made to test the modeling of electric current with Direct Coulomb Summation on Nvidia GPU's. It is using 1.2 million dipole charges in stacked radial loops to model electric current. The simulations were computed on a GTX 560 over a few days. In general, the video uses Coulomb's law to compute an large 321x321x321 observational cube of data. The dataset is then sent to a ray tracer which produces the images in the video. The background colors show the potential energy...

Todd Smith on "The PerkinElmer Omics Laboratory" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Julien Tremblay on "Evaluation of multiplexed 16S rRNA microbial population surveys using Illumina MiSeq platform" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Ze Peng on "Fosmid Cre-LoxP Inverse PCR Paired-End (Fosmid CLIP-PE), A Novel Method for Constructing Fosmid Pair-End Library" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.

Kamlesh Patel on "Preparation of nucleic acid libraries for personalized sequencing systems using an integrated microfluidic hub technology" at the 2012 Sequencing, Finishing, Analysis in the Future Meeting held June 5-7, 2012 in Santa Fe, New Mexico.