Date: 20121204
Course: Protein Prediction 2
Title: SNP effect 1
Speaker: Burkhard Rost

Fission yeast are thought to assemble their cytokinetic actomyosin rings from actin filaments nucleated at myosin-containing nodes around the cell equator. Using an improved actin-binding probe, Huang et al. find that actin cables are nucleated all over the cortex of mitotic fission yeast and are transported to the division site for incorporation into the contractile ring. This biosights episode presents the paper by Huang et al. from the November 26, 2012, issue of The Journal of Cell...

Date: 20121120
Course: Protein Prediction 2
Title: Predict localization 3
Speaker: Burkhard Rost

Date: 20121113
Course: Protein Prediction 2
Title: Predict localization 2
Speaker: Burkhard Rost

The mechanical properties of the extracellular matrix are known to regulate the migration of single cells, but whether substrate stiffness also affects collective cell migration is unclear. Ng et al. reveal that epithelial sheets move faster on stiffer matrices due to increased myosin contractility and mechanical coupling through cell-cell adhesions. This biosights episode presents the paper by Ng et al. from the October 29, 2012, issue of The Journal of Cell Biology and includes an...

Date: 20121106
Course: Protein Prediction 2
Title: Introduction to Protein Function 2
Speaker: Burkhard Rost