biosights: January 21, 2013 - How cell shape changes unfold

submitted by: JCB
Under certain conditions, cells form protrusions that oscillate rapidly around the cell periphery. Kapustina et al. reveal that these oscillatory protrusions, which may be related to processes involved in amoeboid cell migration, are driven by the cyclic folding and unfolding of the plasma membrane and its underlying actin cortex. This biosights episode presents the paper by Kapustina et al. from the January 7, 2013, issue of The Journal of Cell Biology and includes an interview with lead...

Around the Nucleus

submitted by: ahernk

This video is a surreal presentation of a Metabolic Melody by Kevin Ahern ( for more info). The tune is The Beatle's "Across the Universe." The lyrics and video are by Kevin Ahern and the recording is by David Simmons

Endothelin-1 is a transcriptional target of p53 in epidermal keratinocytes and regulates UV induced melanocyte homeostasis

submitted by: arup.indra
Keratinocytes contribute to melanocyte activity by influencing their microenvironment, in part, through secretion of paracrine factors. Here we discovered that p53 directly regulates Edn1 expression in epidermal keratinocytes and controls UV-induced melanocyte homeostasis. Selective ablation of EDN1 in murine epidermis (EDN1ep-/-) does not alter melanocyte homeostasis in newborn skin but decreases dermal melanocytes in adult skin. Results showed that keratinocytic EDN1 in a non-cell...
Authors: Daniel J. Coleman, Gitali Ganguli-Indra, Stephen Hyter, Arup Indra, Steven Ma, Gary F. Merrill, Masashi Yanagisawa

20130117 - Protein Prediction 2 - Burkhard Rost - Protein-DNA/RNA interaction

submitted by: rostlab

Date: 20130117
Course: Protein Prediction 2
Title: Protein-DNA/RNA interaction
Speaker: Burkhard Rost

20130115 - Protein Prediction 2 - Andrea Schafferhans - Protein Ligand Interactions

submitted by: rostlab

Date: 20130115
Course: Protein Prediction 2
Title: Protein Ligand Interactions
Speaker: Andrea Schafferhans

20130110 - Protein Prediction 2 - Burkhard Rost - Predict protein interactions 2

submitted by: rostlab

Date: 20130110
Course: Protein Prediction 2
Title: Predict protein interactions 2
Speaker: Burkhard Rost