This video shows how to install and use the BioBar toolbar on Firefox. This is a nifty addition to the browser that makes accessing many of the usual online databases and tools very easy. It also allows you to easily run a search at these databases without having to navigate to the website first. BioBar can be found at biobar.mozdev.org and was written by Jawahar Swaminathan at the EBI.

This video was produced by GILDA and INFN to show the use of Rosetta protein-folding software on the EUChinaGRID cyberinfrastructure via the GENIUS grid portal.

Background The ability to predict antibody binding sites (aka antigenic determinants or B-cell epitopes) for a given protein is a precursor to new vaccine design and diagnostics. Among the various methods of B-cell epitope identification X-ray crystallography is one of the most reliable methods. Using these experimental data computational methods exist for B-cell epitope prediction. As the number of structures of antibody-protein complexes grows, further interest in prediction...

Background The glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) evolved from a common ancestor. Still not completely understood is how specificity for glucocorticoids (e.g. cortisol) and mineralocorticoids (e.g. aldosterone) evolved in these receptors. Results Our analysis of several vertebrate GRs and MRs in the context of 3D structures of human GR and MR indicates that with the exception of skate GR, a cartilaginous fish, there is a...

Andy McCammon discusses "Computational Science and Drug Discovery" at The Minority-Serving Institutions Cyberinfrastructure Institute (MSICI2) Preliminary Program at the San Diego Supercomputing Center, University of California San Diego La Jolla, California | June 26-29, 2006

Kim Binsted presents "Computational Astrobiology" at The Minority-Serving Institutions Cyberinfrastructure Institute (MSICI2) Preliminary Program at the San Diego Supercomputing Center, University of California San Diego La Jolla, California | June 26-29, 2006