Cytoskeletal Motor Proteins by Ron Vale, July 2007 - Part 1: Introduction to Motor Proteins (43:13)

submitted by: video_collector
Molecular motor proteins are fascinating enzymes that power much of the movement performed by living organisms. In the first part of this lecture, I will provide an overview of the motors that move along cytoskeletal tracks (kinesin and dynein which move along microtubules and myosin which moves along actin). The main focus of this lecture is on how motor proteins work. How does a nanoscale protein convert energy from ATP hydrolysis into unidirectional motion and force production? What tools...

Protein Dynamics Studies of Structure-Switching in Lymphotactin

submitted by: MaxShokhirev

What is lymphotactin and why do we care?
Coarse-Grained Molecular Dynamics (MD).
How can we use MD to study Lymphotactin?
Creating an online user-friendly coarse-grained molecular dynamics tool to help the next generation of scientists.

Protein Secretion and Vesicle Traffic by Randy Schekman - Part 1: Genetic Dissection of the Secretory Pathway (36:35)

submitted by: video_collector
Protein secretion is executed by a cellular pathway involving the delivery of membrane and soluble secretory proteins in vesicles that capture newly-synthesized proteins assembled in the endoplasmic reticulum (ER) and sorted in the Golgi apparatus. Vesicles fuse with the plasma membrane resulting in the discharge of soluble molecules to the cell exterior and integration of vesicle membrane proteins and lipids in the cell surface. Baker's yeast cells grow by vesicle fusion and secretion at...

INCONTINENTIA PIGMENTI

submitted by: camdic
Incontinentia pigmenti, is a rare genodermatosis, also called Bloch-Sulzberger syndrome or Bloch-Siemens, that shows early at birth or in the neonatal period. In its classical form, the cutaneous symptomatology develops through three steps. 1st step, with evidence of injuries, of erythematic-vescicular-blistered kind and one wave after another, linearly positioned and involving upper body and limbs;haematic hypereosinophilia is also present. 2nd step, that pops up between the second and...

Stem Cells: Biology and Promise for Regenerative Medicine by Elaine Fuchs, Jan. 2007 - Part 1: Introduction to Stem Cells and Ethical Issues (35:11)

submitted by: video_collector
During embryogenesis, a single fertilized oocyte gives rise to a multicellular organism whose cells and tissues have adopted differentiated characteristics or fates to perform the specified functions of each organ of the body. As embryos develop, cells that have acquired their particular fate proliferate, enabling tissues and organs to grow. Even after an animal is fully grown, however, many tissues and organs maintain a process known as homeostasis, where as cells die, either by natural...