The New Oral Anticoagulants in Clinical Practice

submitted by: WentzMR
Dr. Wilson Gonsalves, a Hematology Fellow, and Dr. Mrinal Patnaik, an Assistant Professor of Hematology and Oncology at Mayo Clinic in Rochester, MN, share data from their manuscript appearing in the May 2013 issue of Mayo Clinic Proceedings on the development of 3 new alternatives to the anticoagulant, Warfarin, that promise fewer food/drug interactions and do not require therapeutic monitoring. Available at: http://tinyurl.com/bnrxc2c

Weight loss, weight maintenance, and adaptive thermogenesis

submitted by: stefancamps
Background: Diet-induced weight loss is accompanied by adaptive thermogenesis, ie, a disproportional or greater than expected reduction of resting metabolic rate (RMR). Objective: The aim of this study was to investigate whether adaptive thermogenesis is sustained during weight maintenance after weight loss. Design: Subjects were 22 men and 69 women [mean 6 SD age: 40 6 9 y; body mass index (BMI; in kg/m2): 31.9 6 3.0]. They followed a very-low-energy diet for 8 wk, followed by a...
Authors: Stefan Camps, Sanne Verhoef, Klaas Westerterp

Fruit, Mediterranean-style, and high-fat and -sugar diets are associated with the risk of night sweats and hot flushes in midlife

submitted by: gcmherber
Background: Diet has been suggested to be a potential risk factor for vasomotor menopausal symptoms (VMS), i.e. hot flushes and night sweats. Objective: We investigated the associations between dietary patterns and risk of VMS using data from mid-aged women born between 1946 and 1951 in the Australian Longitudinal Study on Women’s Health. Design: A prospective cohort study of 6,040 women with a natural menopause, who were followed up at three-year intervals over nine years. Dietary...
Authors: GCM Herber-Gast

Variant Visualizer Tutorial

submitted by: RGD.Videos

The examination of SNPs has undergone a recent change, and in response to this change, RGD has released the new Variant Visualizer tool (VarVis), taking the place of the old SNPlotyper tool. VarVis is a visualization and analysis tool for sequence variation. The data currently contains 22 rat strains sequenced by 4 independent labs.

Atrial Fibrillation in the 21st Century

submitted by: WentzMR
Dr. Arthur Menezes from the John Ochsner Heart and Vascular Center in New Orleans, LA, examines the risk factors of atrial fibrillation in an article appearing in the April 2013 issue of Mayo Clinic Proceedings, most notably involving metabolic syndrome, obstructive sleep apnea, alcohol consumption, extreme exercise, increased vitamin D, and possibly Omega-3 Polyunsaturated Fatty Acids. Available at: http://tinyurl.com/d8qsnfm

Newly Diagnosed Symptomatic Multiple Myeloma: (mSMART) Consensus Guidelines 2013

submitted by: WentzMR

Dr. Joseph Mikhael, a Hematologist from Mayo Clinic in Arizona shares results of a consensus guideline appearing in the April 2013 issue of Mayo Clinic Proceedings, which provides a rational, safe, and effective update to the changing field of multiple myeloma treatment. Available at: http://tinyurl.com/c7s3jbv