Firing up innate immunity to stop asthma attacks

submitted by: mdanderson
The National Institutes of Health will provide $2.4 million to an MD Anderson researcher to advance a completely new approach to stifling asthma attacks. Scott Evans, M.D., of MD Anderson's Department of Pulmonary Medicine, was named an NIH New Innovator for his proposal to jump-start a rapid immune response to stymie viral infections before they can provoke asthma attacks. "Asthma affects 8 percent of Americans -- 26 million adults and children -- and its incidence continues to grow for...

Use it or lose it: Eating and swallowing exercises show benefit in throat cancer patients

submitted by: mdanderson

Kate Hutcheson, Ph.D., assistant professor in the Department of Head and Neck Surgery, discusses a new study examining the benefits of swallowing and eating exercises for patients undergoing radiation and chemotherapy for head and neck cancers.

Why are HPV-related oral cancers on the rise?

submitted by: mdanderson

The number of oral cancer cases is increasing significantly due largely to the human papillomavirus (HPV), a sexually transmitted disease that's most commonly spread through oral sex.

By 2020, HPV may cause more cases of throat cancer than cervical cancer.

Watch Erich Sturgis, M.D., professor of Head and Neck Surgery at MD Anderson, talk about why HPV-related oral cancers, including throat cancer, are becoming more common.

Genome-wide association study of chronic periodontitis in a general German population

submitted by: ateumer
Aim: To identify loci associated with chronic periodontitis through a genome wide association study (GWAS). Materials and Methods: A GWAS was performed in 4032 individuals of two independent cross-sectional studies of West Pomerania (SHIP n=3365 and SHIP-TREND n=667) with the different periodontal case definitions. Samples were genotyped with the Affymetrix Genome-Wide Human SNP Array 6.0 or the Illumina Human Omni 2.5 array. Imputation of the HapMap as well as the 1000 Genomes based...
Authors: A Teumer, B Holtfreter, U Völker, A Petersmann, M Nauck, R Biffar, H Völzke, HK Kroemer, P Meisel, G Homuth, T Kocher

Horizontal ridge augmentation of the atrophic anterior maxilla using rhBMP-2/ACS or autogenous bone grafts: a proof-of-concept randomized clinical trial.

submitted by: rumoreno
AIM: To compare the effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) in an absorbable collagen sponge carrier (ACS) with autogenous bone graft for augmentation of the edentulous atrophic anterior maxilla. METHODS: Twenty-four subjects were enrolled in a randomized, controlled, parallel-group, open-label clinical trial. Subjects either received rhBMP-2/ACS (1.5 mg/ml) or particulated autogenous bone harvested from the mandibular retromolar region. A titanium-mesh was used...
Authors: Rubens Freitas

Geospatial Exposure to Point-of-Sale Tobacco: Real-time craving and smoking-cessation outcomes

submitted by: tomkirchner
Background: Little is known about the factors that drive the association between point-of-sale marketing and behavior, because methods that directly link individual-level use outcomes to real-world point-of-sale exposure are only now beginning to be developed. Purpose: Daily outcomes during smoking cessation were examined as a function of both real-time geospatial exposure to point-of-sale tobacco (POST) and subjective craving to smoke. Methods: Continuous individual geospatial location data...
Authors: Thomas Kirchner, Jennifer Cantrell, Andrew Anesetti-Rothermel, Ollie Ganz, Donna Vallone, David Abrams