Science Behind the News: Allergies

submitted by: nsf

Seasonal Allergies affect more than 40 million Americans each year. Plant biologist Dr. Kristina Stinson of Harvard University explains how allergies affect the body, and why warmer weather could lead to longer, more severe allergy seasons. "Science Behind the News" is produced in partnership with NBC Learn.

Provided by the National Science Foundation & NBC Learn

Silencing the Menkes Copper-Transporting ATPase (Atp7a) Gene in Rat Intestinal Epithelial (IEC-6) Cells Increases Iron Flux via Transcriptional Induction of Ferroportin 1 (Fpn1)

submitted by: jfcollins
The Menkes copper-transporting ATPase (Atp7a) gene is induced in rat duodenum during iron deficiency, consistent with copper accumulation in the intestinal mucosa and liver. To test the hypothesis that ATP7A influences intestinal iron metabolism, the Atp7a gene was silenced in rat intestinal epithelial (IEC-6) cells using short hairpin RNA (shRNA) technology. Perturbations in intracellular copper homeostasis were noted in knockdown cells, consistent with the dual roles of ATP7A in pumping...
Authors: Sukru Gulec, James F. Collins

DIETARY MAGNESIUM INTAKE IS INVERSELY ASSOCIATED WITH MORTALITY IN ADULTS AT HIGH CARDIOVASCULAR RISK

submitted by: Marta Guasch
The relation between dietary magnesium intake and cardiovascular disease or mortality has been evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular risk. The aim of this study was to assess the association between magnesium intake and cardiovascular disease and mortality risk, in a Mediterranean population at high cardiovascular risk with high average magnesium...
Authors: Marta Guasch-Ferré, Mònica Bulló, Ramon Estruch, Dolores Corella, Miguel A Martínez-González, Emilio Ros, Maribel Covas, Fernando Arós, Enrique Gómez-Gracia, Miquel Fiol, José Lapetra, Miguel A Muñoz, Lluís Serra-Majem, Nancy Babio, Xavier Pintó, Rosa M Lamuela-Raventós, Valentina Ruiz-Gutíerrez, Jordi Salas-Salvadó

The addition of soft tissue replacement grafts in plastic periodontal and implant surgery: critical elements in design and execution

submitted by: Otto Zuhr
Soft tissue replacement grafts have become a substantial element to increase tissue volume in plastic periodontal and implant surgery. Autogenous subepithelial connective tissue grafts are increasingly applied in aesthetic indications like soft tissue thickening, recession treatment, ridge preservation, soft tissue ridge augmentation and papilla reconstruction. For the clinical performance of connective tissue graft harvesting and transplantation, a fundamental understanding of the anatomy...
Authors: Daniel Bäumer, Markus Hürzeler, Otto Zuhr

Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial

submitted by: efung
BACKGROUND: Patients with thalassemia major (Thal) frequently have low plasma zinc, which has been associated with low bone mass. OBJECTIVE: The objective was to determine the effect of zinc supplementation on bone mass in patients with Thal. DESIGN: Forty-two subjects (21 females aged 10-30 y) with Thal and low bone mass were randomly assigned to receive 25 mg Zn/d or placebo. Bone mineral content (BMC) and areal bone mineral density (aBMD) were assessed by using dual-energy X-ray...
Authors: Ellen B. Fung, Janet L. Kwiatkowski, James N. Huang, Ginny Gildengorin, Janet C. King, Elliott P. Vichinsky

Maternal knowledge following nutrition behavior change communication is conditional upon both health workers’ knowledge and knowledge sharing efficacy in rural Haiti

submitted by: mduduzi
In the context of a food assistance program in rural Haiti, we developed measures of the effectiveness of community health worker (CHW)-delivered behavior change communication (BCC). We administered knowledge tests to 954 mothers and 38 CHWs to define 4 measures: CHW knowledge, maternal knowledge, knowledge-sharing efficacy (proportion of CHW knowledge shared), and shared correct knowledge between the CHWs and the mothers with whom they interacted. On the basis of the tests, CHWs had high...
Authors: Mduduzi Mbuya