Danger from the Wild: HIV, Can We Conquer It? by David Baltimore, Feb. 2007 - Part 1: Introduction to Viruses: HIV and Non-equilibrium Viruses (34:06)

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In this set of lectures, I describe the threat facing the world from the human immunodeficiency virus (HIV) and a bold proposal on how we might meet the challenge of eliminating this disease by engineering the immune system. In part 1, I provide a broad introduction to viruses, describing their basic properties and my own history of studying the replication RNA viruses which led to the discovery of reverse transcriptase. I also illustrate the distinguishing features of equilibrium viruses...

Intracellular Parasitism by Trypanosoma cruzi and Leishmania by Norma Andrews, April 2007 - Part 1: Trypanosoma cruzi and Chagas' Disease (19:23)

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Trypanosoma cruzi and Leishmania are closely related intracellular protozoan parasites that cause serious diseases throughout the world. In the first part of this lecture, I will present background material on the biology of Trypanosoma cruzi and the history of its discovery as an important agent of human disease in Latin America. I will also discuss the main characteristics of the disease, and the current efforts to stop human transmission. For more information see:...

Plant Viruses and Crops by Roger Beachy, April 2008 - Part 1: Cell and Molecular Biology of Plant Virus Infection: Early Events and Mechanisms of Pathogenesis

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This seminar describes the cell and molecular biology of plant virus infection. The first lecture will discuss how virus replication centers are set up in plants and how viruses use host cell mechanisms to facilitate cell to cell movement and eventual pathogenesis.

For further information see: http://www.ascb.org/ibioseminars/Beachy/Beachy1.cfm

Apicomplexan Parasites, Pathogen Genome Informatics, and the Evolution of Eukaryotic Organelles by David S. Roos, May 2008 - Part 1: How to build a parasite

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There are more than 5000 species of single-celled eukaryotes in the biological phylum known as the Apicomplexa, including the parasites responsible for malaria, neurological birth defects, and opportunistic infections associated with HIV/AIDS. These ancient protozoa provide a unique window into the evolution of subcellular organelles that have long fascinated cell biologists. Familiar features help to elucidate the origins, functions and design parameters for the secretory pathway,...

Emergence of Azole Resistance in Aspergillus fumigatus and Spread of a Single Resistance Mechanism.

submitted by: nelleke
Background Resistance to triazoles was recently reported in Aspergillus fumigatus isolates cultured from patients with invasive aspergillosis. The prevalence of azole resistance in A. fumigatus is unknown. We investigated the prevalence and spread of azole resistance using our culture collection that contained A. fumigatus isolates collected between 1994 and 2007. Methods and Findings We investigated the prevalence of itraconazole (ITZ) resistance in 1,912 clinical A. fumigatus...
Authors: Eveline Snelders, Henrich a. l. van der Lee, Judith Kuijpers, Anthonius j. m. m. Rijs, János Varga, Robert a. Samson, Emilia Mellado, A. rogier t. Donders, Willem j. g. Melchers, Paul e. Verweij

Research on Aging: Successful Cognitive and Emotional Aging

submitted by: sjanderson

Successful cognitive and emotional aging with noted expert Dr. DilipJeste.