Part II - Benefits of CSR & Design

submitted by: asantos
2 CSR BENEFITS FOR THE COMPANY 2.1 Increase in Profits A report released by Goldman Sachs (GSSustain, 2007) on six industrial sectors – energy, mining, steel, food, beverages and media – found that companies considered leaders in implementing environmental, social and governance policies designed to create sustained competitive advantage had outperformed the overall stock market by 25 per cent since August 2005. Within their own sectors, 72 per cent of these leading companies had...
Authors: Aguinaldo dos Santos, Carlo Vezzoli, Sara Cortesi

Design and Testing of Protein Combinatorial Libraries - Part 1: Introduction to Protein Design by Computation (31:09)

submitted by: video_collector
In this lecture, I discuss the challenges of designing new proteins that fold into a particular structure or perform a particular function. One method is to computationally design a protein based solely upon our knowledge of amino acids and protein folding, a hard task but one which has had recent successes. Another approach is to screen combinatorial libraries of proteins for a desired function. In particular, I will discuss how structure-based computational methods can allow for high...

The Origin of Vertebrates - Part 1: The Origin of the Vertebrate Nervous System: The Hemichordat

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Modern cell and developmental biology has a lot to contribute to our understanding of the deep history of animal origins, which until recently has been largely the province of paleontology. In this set of lectures, I hope to show how recent studies by a very small group of scientists on a virtually unknown phylum of marine organisms, the hemichordates, has helped explain some of the major mysteries of the origin of vertebrates. This is a tour of not only vertebrate origins but the...

Role of the Neural Crest in Vertebrate Development and Evolution by Nicole Le Douarin, March 2008 - Part 1: The Quail Chick Marker System and Its Use to Study the Ontogeny of the Neural Crest (24:45)

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The neural crest (NC) is a transitory structure of the Vertebrate embryo. It forms when the neural tube closes through the epithelio- mesenchymal transition of the cells in the joining neural folds. Its constitutive cells are endowed of migratory capacities and are highly pluripotent. NC cells migrate in the developing embryo along definite pathways, at precise periods of time during embryogenesis and settle in elected sites in the body where they develop into a large of cell types. The...

Tuberculosis: A Persistent Threat to Global Health - Part 1: Tuberculosis: The Once and Future Plague (27:33)

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Human population growth and urbanization have accelerated dramatically in recent centuries, providing unprecedented opportunities for microbes that use our bodies as vehicles for their own propagation and transmission. These conditions have led to the emergence of virulent new pathogens and the increased prevalence of "classic" scourges, such as Mycobacterium tuberculosis. This tenacious microbe is transmitted via infectious aerosols produced by individuals with pulmonary tuberculosis....

The Dynamic Bacterial Cell: Part 1: Dynamics of Bacterial Chromosome Organization, Segregation, and Cytokinesis (34:32)

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Most bacterial cells have their genes arranged in a single circle of DNA. The circle of DNA plus some attached proteins is referred to as the bacterial chromosome. Up until quite recently, it was thought that the chromosome in the tiny bacteria cell resembled a tangled ball of yarn. It is now known that multiple factors cooperate to condense DNA into a highly dynamic assembly of supercoiled loops. Although there is variability in the lower levels of chromosome structure, the global...